豫北地区食管癌根治术后复发转移临床相关因素分析.pdfVIP

-tE 琶· J Med Res , Oct 2012 , Vo 1. 41 No.10 豫北地区食管癌根治术后复发转移临床相关因素分析 郭晓鹤朱艳丽韩宇 摘 要 目的 分析食管癌根治术后复发转移时间及危险因素。方法 回顾性分析笔者医院 2008 年 1 月- 2010 年 12 月间 60 例食管癌根治术后复发转移患者的临床病理资料，分析可能影响食管癌根治术后复发转移的相关因素。结果 术后 1 ， 2 ， 3 ，5 年 累积复发转移率分别为 56.4% 、 83.3% 、 89.7% 、96.4% 。肿瘤大小、内镜分型、分化程度、病理分型、TNM 分期、术后放疗或静脉化 疗与术后复发转移显著相关(P 值分别为 0.002 ， 0.015 ， 0.0∞，0.000 ， 0.000 ， 0.025) 。结论 肿瘤大小、淋巴结转移、TNM 分期是预 测食管癌根治术后复发转移的独立因素(P 值分别为=0.015 ， 0.000 ， 0.003) 。食管癌术后复发转移大部分发生在术后 2 年内，肿瘤 大小、分化程度、淋巴结转移和 TNM 分期是预测早期复发转移的主要影响因素(P 值分别为 0.035 ， 0.002 ， 0.000 ， 0.046) 。 关键词 食管癌根治术复发转移 Analysis of Clinical Related Factors of Recurrence and Metastasis of Esophageal Cancer after Radical Gastrectomy in Area of Yubei of Henan Province. Guo Xiaohe , Zhu Yanli ,Han Yu. The First 明liated Hospital 01 Xinxiang Medical University ,Henan 453100 , China Abstract Objective To explore the occurance and risk factors of recurrence and metastasis of esophageal cancer after radical gas- trectomy. Methods From January 2008 to December 2010 , the clinic palhological data of 60 patients with recurrence and metastasis of e- sophageal cancer after radical gastrectomy in my hospital were analyzed. Results After the surge町， The 1 ,2 ,3 ,5 - year accumulation re- crudescence transfer rate respectively was 56. 4% , 83.3% , 89.7% , 96.4% respactively. The tumor sizes , endoscopic classification , dif- ferentiation grade the pathology tpye , TNM stages , radiotherapy or chemotherapy were independent factors that affected recurrence and me- tastasis of esophageal cancer after radical gastrectomy( P =0.002 ,0.015 ,0.000 ,0.000 ,0.000 ,0.025). Conclusion The tumor size , lymph node metastasis ,TNM stages were the independent risk factors to predict the recurrence and metastasis of esophageal cancer after radical gastrectomy( P =0.