131碘治疗甲状腺功能亢进并发房颤临床效果观察.docVIP

精品论文 参考文献 131碘治疗甲状腺功能亢进并发房颤临床效果观察 王晓燕，纪建松，朱丽萍，徐丽珍，蔡杰 [摘 要]目的：分析131碘治疗甲状腺功能亢进并发房颤的临床效果。方法：收集我院2012年1月-2013年12月期间诊治的甲状腺功能亢进并发房颤患者89例作为研究对象，以随机数字表分组的方式分为试验组（45例）与对照组（44例），对照组患者采用常规抗甲状腺药物他巴唑治疗，试验组采用131碘治疗，对两组患者的整体治疗效果、T3、T4、心率改善情况、不良反应发生率进行分析对比。结果：研究结果显示，试验组患者的整体治疗效果明显高于对照组(Plt;0．05)，T3、T4、心率改善情况明显优于对照组(Plt;0．05)，不良反应发生率明显低于对照组(Plt;0．05)。结论：131碘治疗甲状腺功能亢进并发房颤具有良好的临床疗效，能有效提高患者的整体治疗效果，促进T3、T4、心率改善，降低不良反应发生率，值得在临床应用上推广。 [关键词]131碘 甲状腺功能亢进 房颤 临床效果 DOI:10.3760/cma.j.issn.0376-2491.2015.16.005 作者单位：王晓燕，纪建松，朱丽萍，323000，浙江省丽水市，浙江省丽水市中心医院；325035，浙江省温州市，温州医科大学附属第五医院 The Clinical Effect of 131 Iodine in the Treatment of Thyroid Function Hyperfunction Complicated with Atrial Fibrillation Wang Xiaoyan, Ji Jiansong, Zhu Liping, Xu Lizhen, Cai Jie Abstract: Objective To analyze of the clinical effect of 131 iodine treatment in thyroid function hyperfunction with atrial fibrillation. Methods 89 cases of thyroid function hyperthyroidism complicated with atrial fibrillation from January 2012 to December 2013 were collected as the research object and were divided into the experimental group(45 cases) and the control group (44 cases). The control group were treated by routine anti-thyroid drugs-methimazole treatment while the treatment group were treated with 131 iodine. The overall treatment effect of the patients in the two groups, their T3, T4 index, improved heart rates and the incidence of ad verse reactions were compared. Results The results showed that the overall therapeutic effect of the experimental group patients was obviously higher than that of control group (P lt; 0.05); T3, T4 and improve heart rate in the experimental group were significantly better than that of control group (P lt; 0.05); the incidence of adverse reactions in the experimental group was obviously lower than the control group (P lt; 0.05). Conclusion 131 iodine is effective in the treatment of thyroid function hyperfunction complicated with atrial fibrillation. It can effectively improve the patien