胸痹通胶囊对颈动脉粥样硬化斑块的临床疗效.docVIP

精品论文 参考文献 胸痹通胶囊对颈动脉粥样硬化斑块的临床疗效 　石玉国1 李康2 林扬眉3 　　（1山东省安丘市人民医院 山东 潍坊 262100） 　　（2山东省潍坊市奎文区妇幼保健院 山东 潍坊 261041） 　　（3潍坊护理职业学院 山东 潍坊 262500) 　　【摘要】 目的：观察胸痹通胶囊治疗颈动脉粥样硬化斑块的疗效。方法：50例颈动脉粥样斑块患者，随机分为治疗组和对照组，治疗组25例应用辛伐他汀加胸痹通胶囊治疗，对照组25例给予口服辛伐他汀，治疗6个月后，观察疗效。结果：经6个月治疗后，治疗组颈动脉IMT、血脂较治疗前降低，且优于对照组，有显著差异(Plt;0.01)，中医证候积分疗效高于对照组(Plt;0.01)。结论：胸痹通胶囊具有良好的抗动脉粥样硬化作用。 　　【关键词】颈动脉粥样硬化；中医药疗法；颈动脉内膜中层厚度；胸痹通胶囊 　　【中图分类号】R543.4 【文献标识码】A 【文章编号】2095-1752（2015）09-0035-02 　　Xiongbitong capsule on carotid atherosclerotic plaques of clinical research Shi Yuguo The Peoples Hospital of Anqiu City, Shandong Province, Weifang 262100, China; Li kang. kuiwen Maternal and Child Health Care of Weifang City, Shandong Province, Weifang 261041, China; Lin Yangmei. Nursing Vocational College of Weifang City, Shandong Province, Weifang 262500, China 　　【Abstract】Objective: To observe the Xiongbitong capsule curative effect for the treatment of carotid atherosclerotic plaques. Methods: chooce 50 patients with carotid artery atheromatous plaque, were randomly divided into treatment group and control group, treatment group (25 cases) application simvastatin and Xiongbitong capsule treatment, other 25 cases were given oral simvastatin. Results: After treatment for 6 months, the treatment group the carotid IMT, blood lipid, before the treatment is reduced, and better than the control group, there were significant differences (P lt; 0.01). Conclusion: The obstruction of tong capsule has good resistance effect to atherosclerosis.sustainable development of disinfection supply center, is worthy of popularization and application. 　　【Key words】Carotid atherosclerosis; Traditional Chinese Medicine Therapy; Obstruction of tong capsule 　　动脉粥样硬化及其不稳定斑块是引起心脑血管急症的重要危险因素。颈动脉是最易受累的大血管之一，颈动脉粥样硬化即指双侧颈总动脉、颈总动脉分叉处及颈内、外动脉颅外段血管壁僵硬，内膜下脂质沉积、斑块形成及管腔狭窄[1]。颈动脉粥样硬化程度与缺血性脑卒中的发生密切相关[2]。对其进行早期干预可减轻或逆转动脉粥样硬化，减少心脑血管病的发生率。作者采用胸痹通胶囊联合辛伐他汀治疗颈动脉粥样硬化25例，取得了一定的效果。 　　1.资料与方法 　　1.1 一般资料 　　选取2012-2013年我院就诊病人共50例，均