乳酸菌阴道胶囊治疗细菌性阴道病临床疗效观察分析.docVIP

精品论文 参考文献 乳酸菌阴道胶囊治疗细菌性阴道病临床疗效观察分析 初华 （辽宁省沈阳市和平区妇婴医院 110005） 【中图分类号】R711 【文献标识码】A【文章编号】1672-5085（2012）49-0188-02 【摘要】 目的 观察乳酸菌阴道胶囊与甲硝唑栓治疗细菌性阴道病临床疗效。方法 将112例细菌性阴道病患者按1.15:1随机分为治疗组和对照组，治疗组60例、对照组52例，比较两组治愈率及有效率。结果 两组停药1周治疗组、对照组的总有效率分别为85%、86.54%（Pgt;0.05）;治疗组阴道分泌物HPgt;4.5的2例，对照组10例两组治疗结果的差异有显著性（Plt;0.05）。结论 乳酸菌阴道胶囊治疗细菌性阴道病具有疗效好，不易复发，无明显副作用，安全无毒是治疗妇女细菌性阴道病的理想方法。 【关键词】 乳酸菌 阴道炎 Clinical Observation on Treatment of Bacterial Vagina Diseases by Therapy with Lactobacillus Vagina Capsule Shenyang City Heping District Penetration Hospital Chu Hua 110005 【Abstract】Objective: To observe the clinical effect of Lactobacillus vagina capsule and Metronidazole suppositories in treatment of bacterial vagina diseases. Method: Randomly separate the 112 patients into the treatment group and the control group based on a ratio of 1.15:1. The number of people in the treatment group is 60 and in the control group is 50. Compare the cure rate and the efficiency rate of the two groups. Result: After one-week drug withdrawal, the efficiency rates of the treatment group and the control group are 85% and 86.54% (Pgt;0.05); The number of patients whose vaginal fluid Hpgt;4.5 is two in the treatment group while the number is ten in the control group. The difference between the two groupsrsquo; clinical effect is significant (Plt;0.05).Conclusion: Lactobacillus vagina capsule can treat bacterial vagina diseases well with a low risk of relapse. The treatment is also safe and nontoxic and is free from obvious side-effects. It is proved that lactobacillus vagina capsule is an ideal method to treat bacterial vagina diseases. 【Keywords】 Lactobacillus colpitis 细菌性阴道病（bacterialvaginosis BV）是阴道内正常菌群失调所致的一种混合感染，以厌氧菌居多，占外阴、阴道感染40%-50%[1]。若不及时治疗可引起子宫出血、盆腔炎、输卵管炎、不孕、早产、产褥期感染等妇产科并发症，以前临床上应用抗生素抑制细菌生长，由于抗生素在抑制治病菌的同时破坏了阴道正常菌群，容易引起二重感染，并有耐药性问题，治疗反复发作的阴道炎效果较差[2]。乳酸菌阴道胶囊主要成分为活乳菌酸，通过调整阴道菌群治疗阴道炎。我院自2010年1月以来试用乳酸菌阴道胶囊（商品名：延华胶囊，西安华誉制药有限公司生产）治疗细菌性阴道病，获得了良好临床疗效，现报道如下。