乳酸亚铁片治疗缺铁性贫血临床疗效.docVIP

乳酸亚铁片治疗缺铁性贫血临床疗效[摘要] 目的：研究乳酸亚铁片治疗缺铁性贫血的疗效及不良反应。方法：将诊断为缺铁性贫血的56例患者随机分为实验组（31例）及对照组（25例）。实验组用乳酸亚铁片治疗，而对照组用琥珀酸亚铁治疗，比较两者的疗效。结果：两组治疗6周总有效率分别为96.77%及100.00%，两药疗效无统计学差异（P＞0.05）。结论：乳酸亚铁片治疗缺铁性贫血疗效好，胃肠不良反应轻，是治疗缺铁性贫血安全有效的口服铁剂。 [关键词] 乳酸亚铁片；琥珀酸亚铁；缺铁性贫血 [中图分类号] R556.3[文献标识码]A [文章编号]1673-7210（2009）06（b）-059-02 The clinical efficacy of Ferrous Lactate Tablets in the treatment of iron deficiency anemia LUO Guozhen, LI Liping (Deparment of Hemotolgy, Kaiping Central Hospital, Kaiping 529300, China) [Abstract] Objective: To study the clinical efficafy and adverse reactions of Ferrous Lactate Tablets in the treatment of iron deficiency anemia. Methods: Diagnosed with iron deficiency anemia, 56 patients were randomly divided into test group(31 cases) and control group(25 cases). The test group were treated by Ferrous Lactate Tablets, while the control group were treated by Ferrous Succinate, then compared the efficacy of the two groups. Results: The total effective rate of the control group was 96.77% and the test group was 100.00% after 6 weeks. There was no statistical difference between two groups (P＞0.05). Conclusion: The Ferrous Lactate Tablets in treatment of iron deficiency anemia has a good effect, and gastrointestinal adverse reactions of light, the treatment of iron deficiency anemia is safe and effective oral iron. [Key words] Ferrous Lactate Tablets; Ferrous Succinate; Iron deficiency anemia 缺铁性贫血是最常见的一种贫血，发展中国家患病率高达30%～90%[1]。各年龄、性别均可发病，尤为育龄妇女、青少年和婴幼儿的发病率高，而口服铁剂是治疗缺铁性贫血的首选。乳酸亚铁片具有口服吸收好、生物利用度高、疗效好、不良反应小的优点，且药价便宜，是口服铁剂中较佳者。我院为评价其疗效和不良反应，现将我院随访的缺铁性贫血患者的治疗效果总结报道如下： 1 资料与方法 1.1 一般资料 56例缺铁性贫血患者均为我院2004年12月～2008年12月住院和（或）门诊患者。其中，门诊36例，住院20例；年龄在18～65岁，平均40岁；男23例，女33例。随访治疗6周以上者，符合我国缺铁性贫血诊断标准[2]，确诊为缺铁性贫血，病程2个月～1年。 1.2 方法 将病例随机分为实验组（31例）及对照组（25例），两组首先作病因治疗。实验组同时给乳酸亚铁片口服（由四川太极制药有限公司研制提供，每片含铁量19.4 mg），每日2片，每日3次，饭后服。Hb水平达正常范围后改为每日总量3 ～ 4片，维持用药2～3个月，以补充储存铁，同时口服维生素C。对照组服用琥珀酸亚铁片（由南京制药三厂生产，每片含铁量35 mg），每次1片，每日3次，饭后服。治疗开始后每周作1次血细胞分析，以观察客观疗效，同时观察记录患者贫血症状及体