中西医结合治疗糖尿病湿性坏疽80例临床观察.docVIP

中西医结合治疗糖尿病湿性坏疽80例临床观察[摘要] 目的 观察中西医结合治疗糖尿病湿性坏疽的临床疗效。 方法 选择2008年1月～2011年6月在本院住院治疗的糖尿病湿性坏疽患者80例，随机分为治疗组和对照组。治疗组采用降糖+中药口服+清洁换药治疗，对照组采用降糖+清洁换药。 结果 治疗组临床总有效率为95.0%，对照组总有效率为87.5%，两组比较差异有统计学意义（P 0.05）；两组治疗后血液流变学指标比较，差异有统计学意义（P 0.05）。 结论 中西医结合治疗糖尿病湿性坏疽疗效显著，值得在临床上推广应用。 [关键词] 中西医结合；糖尿病；湿性坏疽；疗效 [中图分类号] R587.2 [文献标识码] A [文章编号] 1674—4721（2012）09（c）—0112—02 Clinical observation of 80 cases with diabetic moist gangrene treated by the combination of traditional Chinese and Western medicine WANG Ruzhe FAN Hong Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine in Hebei Province， Cangzhou 061000， China [Abstract] Objective To observe clinical effect of combination of traditional Chinese and Western medicine in the treatment of diabetic moist gangrene. Methods Eighty patients with diabetic moist gangrene in our hospital inpatient from January 2008 to June 2011 were randomly divided into treatment group and control group. Treatment group was given traditional Chinese medicine and oral hypoglycemic and wound care. Control group was given hypoglycemic and wound care. Results Total effective rate of treatment group was 95.0%， total effective rate of control group was 87.5%， there was significant difference （P 0.05）. After treatment， blood rheology indexes differences of the two groups were significant （P 0.05）. Conclusion Combination of traditional Chinese and Western medicine therapy in the treatment of diabetic moist gangrene is significant effect， and it is worthy of clinical application. [Key words] Traditional Chinese and Western medicine； Diabetes； Moist gangrene； Clinical effect 糖尿病坏疽是糖尿病最常见的严重并发症之一，其由于多合并神经病变及末梢血管病变而导致下肢感染、溃疡形成和（或）深部组织的破坏。临床上以肢体末端疼痛、麻木、感染、缺血、溃疡、坏疽为主要特征，导致患者生活质量低，愈后差。笔者通过中西医结合，内治与外治结合，收到了满意疗效，现报道如下： 1 资料与方法 1.1 一般资料 选择2008年1月～2011年6月在沧州中西医结合医院住院治疗的糖尿病湿性坏疽患者80例。根据全国第四届中西医结合治疗周围血管疾病会议（1995年）修订的糖尿病肢体血管病变诊断标准坏疽分级标准：Ⅰ级，坏疽只位于趾部；Ⅱ级，坏疽延及跖趾关节或跖部；Ⅲ级，坏疽延及全足背及踝关节、腿部。将所有患者随机分为两组，治疗组40例，对照组40例。两组患者的一般情况比较见表1。 1.2 诊断标准 全部病例均根据199