31例原发性肺癌患者舌象特征参数及生命质量量表相关性研究.docVIP

31例原发性肺癌患者舌象特征参数及生命质量量表相关性研究摘 要：目的：探讨原发性肺癌患者中医舌象客观化参数与生命质量量表的相关性，为中医/中西医结合治疗肺癌的临床疗效评价提供有中医特色的客观指标。方法:选择气阴两虚型原发性非小细胞肺癌患者作为研究对象。采用ZBOX-Ⅰ型舌象数字化分析仪采集患者的舌象客观参数，并选用EORTC QLQ-C30 V3.0、EORTC QLQ-LC13中文版及KPS量表来测定肺癌患者的生命质量，分析舌象参数与生命质量量表之间的相关性。结果:（1）点刺指数与生命质量量表中失眠之间的简单相关系数较大；（2）舌象参数与生命质量量表之间不具有典型相关性。结论：舌象指标与生命质量量表之间存在一定的相关性，提示舌象客观参数的变化可以作为临床评价中医/中西医结合治疗肺癌疗效的参考指标之一。 关键词：原发性肺癌；舌象参数；生命质量量表；相关性 中图分类号：R734.2 文献标识码：A 文章编号：1673-7717（2011）04-0786-04 Abstract:Objective：Discussing the relationship between the objective of parameter of the tongue image and the quality of life scale of the patients with primary lung cancer，and try to provide objective indicators with Chinese Characteristics for the lung cancer clinical Evaluation by the treatment of Traditional Chinese Medicine / TCM-WM. Methods：Choosing the Patients who were diagnosed as primary none-small cell lung cancer（NSCLC） with deficiency of both Qi and Yin，using the type of ZBOX-I Tongue Digital Analyzer to collect the patients tongue parameters，and choose the EORTC QLQ-C30 V3.0, EORTC QLQ-LC13 to collect their quality of life. Anglicizing the relationship of the tongue parameters and the quality of life. Results：（1）The Simple correlation coefficient between the index of Dianci and the insomnia is greater（2）There is no Typical relationship between the tongue parameters and the quality of life.Conclution：The tongue parameters are certain related with the quality of life,it means the tongue parameters can be used as one of the clinical efficacy indicator to evaluate the lung cancer treatment of TCM or Combining Chinese and Western medicine. Key words:Primary lung cancer；tongue parameters；quality of life；relationship 原发性支气管肺癌是指原发于支气管粘膜和肺泡壁的恶性肿瘤，属于中医“肺积”、“肺岩”、“息贲”范畴。其恶性程度高，生物学特性复杂，现代医学总的治愈率低。中医治疗、中西医结合治疗在改善肺癌患者症状、延长生存期、提高生存质量方面有独特优势【sup】［1］【/sup】。 中医舌诊是临床独具特色的诊断方法之一，也是中医临床判断病情、辨别病证的重要参考依据之一。本课题组在临床观察中也发现舌象在肺癌病情不同时期有明显改变，并与病情严重程度相关。已有研究者观察分析了肺癌患者舌象与血液生化指标之间的相关性【sup】［2-3］【/sup】，但还未见探讨肺癌舌象象客观化参数与生命质量量表之间相关性的文献报道。 本研