药师参与机械瓣膜置换术后妊娠期抗凝药物治疗的探讨.pdfVIP

CHINESECOMMUNITYDOCTORS 论著·社区用药指导 药师参与机械瓣膜置换术后妊娠期抗凝药物治疗的探讨 朱云霞 张梅 653100玉溪市中医医院 doi:10.3969/j.issn.1007-614x.2016.28.6 摘 要 目的：探索药师参与机械瓣膜置换术后妊娠和分娩期患者抗凝治疗的药学实践。方法：药师根据机械瓣膜置 换术后抗凝的权威指南，与临床医师合作，对5例机械瓣膜置换术后妇女在妊娠和分娩期进行抗凝方案的制定和药学 的监测，制定个体化的治疗方案并随时调整。结果：通过对本组5例妊娠妇女全程化药物管理和监测，逐步建立了药 师参与的抗凝治疗规范化工作模式。结论：药师在机械瓣膜置换术后妊娠和分娩期抗凝治疗团队中深入开展规范化药 物治疗和监测方案，可更好地保障患者用药的安全与合理性。 关键词 华法林；抗凝；机械瓣膜置换；妊娠 Investigationofpharmacistsparticipatinginthetreatmentofpregnancyaftermechanicalvalvereplacement ZhuYunxia,ZhangMei TraditionalChineseMedicineHospitalofYuxiCity653100 Abstract Objective:To explore the pharmaceutical practice of anticoagulant therapy by pharmacists participating in the treatment of patients with pregnancy and delivery after mechanical valve replacement.Method:An authoritative guide for pharmacists to anticoagulation after mechanical valve replacement,in cooperation with clinicians,we formulated the anticoagulationplanandthemonitoringofthepharmacyinpregnancyanddeliveryperiodfor 5 casesofwomenafterthe mechanicalvalvereplacementoperation,andtodevelopindividualizedtreatmentprogramsandatanytimetoadjust.Results: Throughthedrugmanagementandmonitoringinthewholeprocessof 5 casesofpregnantwomen,andgraduallyestablisheda pharmacisttoparticipateinthestandardizationofthetreatmentofanticoagulation.Conclusion:Pharmacistsinthemechanical valvereplacementpregnancyanddeliveryperiodaftertheanticoagulationtherapyteamtocarryoutstandardizeddrugtreatment andmonitoringprogram,whichcanbetterprotectthesafetyandrationalityofpatientswithmedication. Keywords Warfarin;Anticoagulation;Mechanicalvalvereplacement;Pregnancy 从2010年1月至今，我们对在我院 安全的平衡点，制定个体化的抗凝强 响。在抗凝方案的选择时通常要根据患 进行产前检查和分娩的5位育龄期换瓣 度。目前临床上最常使用的抗凝剂主要 者的具体情况，综合产科、心胸外科、 妇女进行抗凝方案的制定以及抗凝药物 为华法林和肝素，华法林防止抗凝效果 心内科等多学科