核磁共振和多发性硬化诊断.pdfVIP

Review MRI and the diagnosis of multiple sclerosis: expanding the concept of “no better explanation” Arnaud Charil, Tarek A Yousry, Marco Rovaris, Frederik Barkhof, Nicola De Stefano, Franz Fazekas, David H Miller, Xavier Montalban, Jack H Simon, Chris Polman, Massimo Filippi Although the diagnosis of multiple sclerosis relies on the demonstration of disease dissemination in space and time, Lancet Neurol 2006; 5: 841–52 the exclusion of other neurological disorders is also essential. The limited specifi city of abnormalities disclosed by See Refl ection and Reaction MRI may increase the likelihood of diagnosis of multiple sclerosis in patients aff ected by other disorders. The available page 808 criteria for diagnosis of multiple sclerosis have not taken advantage of the potential of MRI to detect features “not Neuroimaging Research Unit, suggestive” of multiple sclerosis. Recognition of such features in the work-up of patients suspected of having multiple Department of Neurology, Scientifi c Institute and sclerosis may reduce the likelihood of a false positive diagnosis of the disorder in some, while suggesting the correct University Ospedale San alternative diagnosis in other patients. On the basis of this, a workshop of the European MAGNIMS (Magnetic Raff aele, Milan, Italy Resonance Network in Multiple Sclerosis) was held to defi ne a series of MRI red fl a