tace治疗原发性肝癌不同栓塞剂对血常规三系的影响.docVIP

TACE治疗原发性肝癌不同栓塞剂对血常规三系的影响 　　【摘要】 目的 探?肝动脉栓塞化疗术（TACE）治疗原发性肝癌不同栓塞剂对血常规三系的影响。方法 60例原发性肝癌患者， 依据接受栓塞剂的不同分为海藻酸钠组和碘化油组， 每组30例。海藻酸钠组接受海藻酸钠-TACE治疗， 碘化油组接受碘化油-TACE治疗。术前1周及术后第5天抽血检查， 评价血常规三系的情况。结果 ①海藻酸钠组：TACE后第5天血液红细胞（3.8±0.8）×1012/L和血小板（121±62）×109/L较TACE前（4.3±0.8）×1012/L、（166±86）×109/L下降， 差异具有统计学意义（P0.05）。②碘化油组：TACE后第5天血液红细胞（3.8±0.8）×1012/L和血小板（120±68）×109/L较TACE前（4.3±0.9）×1012/L、（167±87）×109/L 　　下降， 差异具有统计学意义（P0.05）。③两组患者TACE后第5天血常规三系比较， 差异均无统计学意义（P0.05）。结论 海藻酸钠和碘化油作为TACE的栓塞剂， 均会导致一定程度的血液红细胞和血小板降低， 但是两者的影响无差异， 总体较为安全。 　　【关键词】 肝动脉栓塞化疗术；原发性肝癌；海藻酸钠；碘化油；血常规 　　DOI：10.14163/j.cnki.11-5547/r.2017.01.027 　　、 　　Effect of differenct embolism agents on routine blood three lines for TACE in treating primary hepatic carcinoma HUANG Wu-kui， WANG Hai-lin， LIU Deng-yao， et al. Department of Interventional Diagnosis and Treatment （Intervention Room）， Xinjiang Uygur Autonomous Region Xinjiang Medical University Affiliated Tumor Hospital， Urumchi 830011， China 　　【Abstract】 Objective To explore effect of differenct embolism agents on routine blood three lines for transcatheter arterial chemoembolization （TACE） in treating primary hepatic carcinoma. Methods A totoal of 60 primary hepatic carcinoma patients were divided by differenct embolism agents into sodium alginate group and iodinated oil group， with 30 cases in each group. The sodium alginate group received sodium alginate-TACE therapy， and the iodinated oil group received iodinated oil-TACE therapy. Serologic examinations was performed on 1 week before operation and 5 days after operation to evaluate routine blood three lines. Results ①The sodium alginate group： with red blood cell 5 days after TACE as（3.8±0.8）×1012/L and blood platelet as （121±62）×109/L， which were lower than （4.3±0.8）×1012/L and （166±86）×109/L before TACE， and their differences had statistical significance （P0.05）. ②The iodinated oil group： with red blood cell 5 days after TACE as （3.8±0.8）×1012/L and blood platelet as （120±68）×109/L， which were all lower than （