心肌型脂肪酸结合蛋白对急性肺栓塞早期危险分层的作用 林玉珍卢育明杜国有黄振炎.docVIP

精品论文 参考文献 心肌型脂肪酸结合蛋白对急性肺栓塞早期危险分层的作用 林玉珍卢育明杜国有黄振炎 林玉珍卢育明杜国有黄振炎 （广州中医药大学附属中山医院528400） 【摘要】目的：本研究选取中山市中医院诊断急性肺栓塞(APE)的患者，选取新型早期生物标记心肌型脂肪酸结合蛋白（H-FABP）探讨其在急性肺栓塞患者早期危险分层中的价值。方法：观察APE 早期H-FABP水平，比较其与心脏血清标记物脑钠肽（BNP）、血清肌钙蛋白（CTNI）的相关性，评估H-FABP对急性肺动脉栓塞早期危险分层的意义，结果：本研究表明，APE 组H-FABP、BNP 较对照组分别有明显差异性（Plt;0.01）及有差异性（Plt;0.05），而APE 组中低危组、中危组、高危组H-FABP、BNP 呈显著递增趋势，且H-FABP 阳性组在不良发生事件（呼吸困难、胸痛、晕厥、咯血）发生率增加。结论：提示H-FABP是APE 患者右室损伤和功能不良的早期标记物，是可用于急性肺栓塞危险分层的生化指标。 【关键词】急性肺动脉栓塞；心肌型脂肪酸结合蛋白；危险分层 【中图分类号】R2 【文献标号】A 【文章编号】1671-8725（2014）12-0018-02 Heart type fatty acid binding protein for early riskstratification in acute pulmonary embolismLin Yuzhen;Lu Yuming;Du Guoyou;Huang Zhenyan（1.Daqing Oilfield General Hospital，HeiLongJiang DaQing,163000）abstract:Objective: For laparoscopic joint choledochoscope plasma lithotripsy in the treatment of intrahepatic bile duct stones of curative effect is analyzed.Methods: 160 patients with intrahepatic bile duct stones can be divided into laparoscopic group and the control group, each of 80 cases of laparoscopicgroup line joint choledochoscope plasma lithotripsy under laparoscopic treatment, the control line of traditional open surgery combined intraoperativecholedochoscope lithotomy treatment, compared two groups of therapeutic effect. Results: the laparoscopic group was the residual stone rate calculiexhausted rate 7.5% 95% and 7.5%, respectively, in thecontrol group was the residual stone rate calculi exhausted rate 28.5% 77.5% and 28.5%, respectively, are similar between the two groups was statisticallysignificant (P lt; 0.05); T tube in blood loss length of hospital stay of laparoscopic group of common bile duct pressure was better than control group,comparing difference to be markedly, with statistical significance (P lt; 0.05). Conclusion: laparoscopic joint choledochoscope plasma lithotripsy in thetreatment of intrahepatic bile duct stones, curative effect is distinct, with a slight trauma Shorter hospitalizat