SARS患者恢复期传染性随访调查.docVIP

SARS患者恢复期传染性随访调查 　 作者：王昆，王波，门可，徐德忠，闫永平 【关键词】 严重急性呼吸综合征 　　【Abstract】AIM： To study the infectiousness of the convalescent patients with severe acute respiratory syndrome (SARS). METHODS: Standardized epidemiological follow-up study questionnaire was adopted in the followup study by phone of the convalescent (1 month after discharge) patients who were reported during April and May 2003 in database of epidemiological individual cases with SARS in Beijing. Data of investigation were processed to build database for statistical and epidemiological analysis. RESULTS: In the 300 cases that were selected randomly, 133 cases (44.3%) who had been diagnosed with SARS were successfully followed up, with a sex ratio of 1∶1.2 and an age range from 15 to 66. 167 cases (55.7%) were lost in the follow-up study. The most common symptom was fever (100%), followed by cough (72.2%), pneumonia on chest radiograph (70.7%), decreased leukocyte counts (66.9%), cold (54.9%), inertia (35.3%), headache (23.3%), aching pain (21.2%), expectoration (9.8%). Ninety-four percent of the 133 SARS cases adopted home isolation after being discharged from hospital, among whom 98 cases (78.4 percent of isolated cases) were isolated for 14 days. The infection control precautions could be divided into 6 categories. None those who had close contacts with convalescent SARS patients were infected. CONCLUSION: The convalescent SARS patients, who are discharged from hospital according to the discharge criteria for SARS patients promulgated by ministry of health, have no obvious infectiousness. 　　【Keywords】 severe acute respiratory syndrome; convalescence; disease transmission, horizontal 　　【摘要】目的： 了解严重急性呼吸综合征（SARS）恢复期患者的传染性.方法： 采用统一制定的流行病学随访调查表，在《北京市SARS流行病学个案调查数据库》中随机抽取300例200304/200305报告的SARS病例进行恢复期（出院后1 mo）电话随访调查，建立数据库进行统计学和流行病学分析.结果： 随机抽取300例中，随访到133例（占443%）确诊SARS的恢复期患者，失访167例（占557%），实际随访率为700 %.133例SARS患者中男女性别比为1∶12，年龄在15~66 yr之间.临床表现发热133例（100%），咳嗽96例（722%），X线胸片肺炎特征94例（707%），白细胞总数减少89例（669%），畏寒73例（549%），乏力