adherence to self-administered tuberculosis treatment in a high hiv-prevalence setting a cross-sectional survey in homa bay, kenya坚持自行结核病治疗艾滋病毒感染率高设置homa湾横断面调查,肯尼亚.pdfVIP
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adherence to self-administered tuberculosis treatment in a high hiv-prevalence setting a cross-sectional survey in homa bay, kenya坚持自行结核病治疗艾滋病毒感染率高设置homa湾横断面调查,肯尼亚
Adherence to Self-Administered Tuberculosis Treatment
in a High HIV-Prevalence Setting: A Cross-Sectional
Survey in Homa Bay, Kenya
1 2 ´ 1 3 1
Fabienne Nackers *, Helena Huerga , Emmanuelle Espie , Apollo Odongo Aloo , Mathieu Bastard ,
1,4 3 2 5 1
Jean-Franc¸ois Etard , Joseph Sitienei , Francis Varaine , Jeremiah Chakaya , Maryline Bonnet
´ `
1 Epicentre, Paris, France, 2 Medecins Sans Frontieres-France, Paris, France, 3 National Leprosy Tuberculosis Program, Nairobi, Kenya, 4 IRD/UMI 233 TransVIHMI,
Montpellier, France, 5 Centre for Respiratory Diseases Research, Kenyan Medical Research Institute, Nairobi, Kenya
Abstract
Background: Good adherence to treatment is crucial to control tuberculosis (TB). Efficiency and feasibility of directly
´
observed therapy (DOT) under routine program conditions have been questioned. As an alternative, Medecins sans
`
Frontieres introduced self-administered therapy (SAT) in several TB programs. We aimed to measure adherence to TB
treatment among patients receiving TB chemotherapy with fixed dose combination (FDC) under SAT at the Homa Bay
district hospital (Kenya). A second objective was to compare the adherence agreement between different assessment tools.
Methods: We conducted a cross-sectional survey amongst a series of new TB patients receiving 6 months of standard TB
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