有哪些信誉好的足球投注网站a putative transcription factor myt2 regulates perithecium size in the ascomycete gibberella zeae一个假定的转录因子myt2调节子囊壳大小的子囊菌赤霉菌属菌.pdfVIP
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a putative transcription factor myt2 regulates perithecium size in the ascomycete gibberella zeae一个假定的转录因子myt2调节子囊壳大小的子囊菌赤霉菌属菌
A Putative Transcription Factor MYT2 Regulates
Perithecium Size in the Ascomycete Gibberella zeae
1 1 1 2 3 3
Yang Lin , Hokyoung Son , Kyunghun Min , Jungkwan Lee , Gyung Ja Choi , Jin-Cheol Kim , Yin-
Won Lee1*
1 Department of Agricultural Biotechnology and the Center for Fungal Pathogenesis, Seoul National University, Seoul, Republic of Korea, 2 Department of Applied
Biology, Dong-A University, Busan, Republic of Korea, 3 Eco-friendly New Materials Research Group, Research Center for Biobased Chemistry, Division of Convergence
Chemistry, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea
Abstract
The homothallic ascomycete fungus Gibberella zeae is a plant pathogen that is found worldwide, causing Fusarium head
blight (FHB) in cereal crops and ear rot of maize. Ascospores formed in fruiting bodies (i.e., perithecia) are hypothesized to
be the primary inocula for FHB disease. Perithecium development is a complex cellular differentiation process controlled by
many developmentally regulated genes. In this study, we selected a previously reported putative transcription factor
containing the Myb DNA-binding domain MYT2 for an in-depth study on sexual development. The deletion of MYT2
resulted in a larger perithecium, while its overexpression resulted in a smaller perithecium when compared to the wild-type
strain. These data suggest that MYT2 regulates perithecium size differentiation. MYT2 overexpression affected pleiotropic
phenotypes including vegetative growth, conidia production, virulence, and mycotoxin production. Nuclear localization of
the MYT2 protein supports its role as a transcriptional regulator. Transcriptional analyses of trichothecene synthetic genes
suggest that MY
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