a qualitative study of provider thoughts on implementing pre-exposure prophylaxis (prep) in clinical settings to prevent hiv infection定性研究提供者暴露前预防思想实现(预科)预防艾滋病毒感染在临床的设置.pdfVIP
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a qualitative study of provider thoughts on implementing pre-exposure prophylaxis (prep) in clinical settings to prevent hiv infection定性研究提供者暴露前预防思想实现(预科)预防艾滋病毒感染在临床的设置
A Qualitative Study of Provider Thoughts on
Implementing Pre-Exposure Prophylaxis (PrEP) in Clinical
Settings to Prevent HIV Infection
1 1 1 2 1
Emily A. Arnold *, Patrick Hazelton , Tim Lane , Katerina A. Christopoulos , Gabriel R. Galindo ,
Wayne T. Steward1, Stephen F. Morin1
1 Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, California, United States of America, 2 HIV/AIDS Division, San Francisco General
Hospital, University of California San Francisco, San Francisco, California, United States of America
Abstract
Background: A recent clinical trial demonstrated that a daily dose tenofovir disoproxil fumarate and emtricitabrine (TDF-
FTC) can reduce HIV acquisition among men who have sex with men (MSM) and transgender (TG) women by 44%, and up
to 90% if taken daily. We explored how medical and service providers understand research results and plan to develop
clinical protocols to prescribe, support and monitor adherence for patients on PrEP in the United States.
Methods: Using referrals from our community collaborators and snowball sampling, we recruited 22 healthcare providers in
San Francisco, Oakland, and Los Angeles for in-depth interviews from May-December 2011. The providers included primary
care physicians seeing high numbers of MSM and TG women, HIV specialists, community health clinic providers, and public
health officials. We analyzed interviews thematically to produce recommendations for setting policy around implementing
PrEP. Interview topics included: assessing clinician impressions of PrEP and CDC guidance, considerations of cost, office
capacity, dosing schedules, and following patients over time.
Results: Little or no demand for PrEP from patients was repo
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