三七总皂甙对兔创伤性肢体深静脉血栓地形成影响.pdf

and C both only had a case 1 level of thrombus formation, the rate of thrombus formation was 16.7%; The group B had 2 cases 2 level of thrombus formations, the formation rate is 28.6%; The group D had 3 cases 1 level of thrombus formation, the formation rate is 42.9%; All of the group E had the thrombus formation, 5 cases are 2 levels of thrombus formations, 1 example 3 levels of thrombus formations, the formation rate is 100%. The medication intervention group’s thrombus formation rate was obviously lower than the model control group, the statistical analysis had significant difference (P 0.05), the long-term medicine intervention group formation rate was lower than the short-term intervention group, but the statistical analysis did not find significant differences (P 0.05), may be effected by the inadequate sample size which included in statistics. Conclusion: Both PNS and LMWH chould lower the blood viscosity and improve the blood hypercoagulable state, they also chould reduce the rate of the formations of traumatic deep venous thrombosis in limbs. the long-term medicine intervention group formation rate was lower than the short-term intervention group, but the statistical analysis did not find significant differences, However, the improvement of post-traumatic blood hypercoagulable state and reduce blood viscosity, both the long-term intervention group are better than short-term intervention group. Key word ：lower limbs Deep vein; thrombosis; PNS; LMWH; animal experiments - 5 - 引 言 [1] 下肢深静脉血栓形成是创伤骨科手术后的常见并发症之一 。据国外 文献报道骨科术后未行预防治疗者创伤性下肢深静脉血栓形成的发生率