120例难治性抑郁症中医征候研究.docVIP

120例难治性抑郁症中医征候研究收稿日期:2009-11-10 基金项目:北京市中医医药科技发展基金资助项目(JJ2005-16) 作者简介:刘杰(1973-),男,江苏徐州人,主治医师,硕士研究生,研究方向:中医内科学。 通讯作者:贾?晓(1966-),男,山西人,教授、主任医师,博士,研究方向:中西医结合精神病学。Tel:010E?mal:jhxlj@vip.省略。 (1.首都医科大学附属北京安定医院,北京 100088;2北京中医药大学附属东直门医院,北京 100700) 摘 要:目的:探讨难治性抑郁症的中医证候特点及辨证分型规律。方法:通过对120例难治性抑郁症患者的临床流行病学调查,采集病史、症状、舌、脉等基本信息,以频数分析、聚类分析、主成分分析的方法分析难治性抑郁症的证候分布规律及证候特点。结果:难治性抑郁症常见症状共36种,出现频率较高的有:忧愁善感、烦躁、神疲乏力、兴趣索然、食欲下降、倦卧少动等,常见辨证分型分为5类:肝郁脾虚、气郁化火、脾肾阳虚、肝郁痰阻、肝郁血瘀。结论:难治性抑郁症与普通抑郁症在证候特点有不同之处。 关键词:难治性抑郁症;中医证候;聚类分析? 中图分类号:R749.41 文献标识码:B 文章编号:1673-7717(2010)04-0723-03 The Analysis of 120 Treat-resistant Depression Patientss TCM Patterns LIU Jie1,JIA Hong?xiao1, ZOU Yi?huai2, WANG Jian?qin1 (1.Beijing An Ding Hospital, Capital Medical University,Beijing 100088, China; 2.Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China) Abstract:?Objective: ?To study the general law of typing and TCM Patterns for treatment-resistant depression according to syndrome differentiation. ?Methods:?Through the epidemiological investigation, by way of epidemiological investigation, We collected the symptoms,physical signs,tongue demonstrations and pulse tracings in 120 patients with treatment-resistant depression, using Frequency and cluster analysis、also with principal component analysis as research discriminant for TCM Patterns. ?Results:?There are 36 species symptoms usually seen in treatment-resistant depression. The most common of them are: incessant worries and miseries , restlessness, fatigue, lose of interest, hebetude, dysorexia, drowsiness and hypokinesia and so on.According to syndrome types, TCM Patterns devided into five category as: stagnation of liver-QI with deficiency of the spleen , stagnatedQItransforming into fire,asdthenic splenonephro-yang , hepatic stagnation and retention of phlegm,hepatic stagnation and blood stasis. ?Conclusion:?Treatment-resistant depression is different in features of TCM Patterns to common de