儿童社区获得性肺炎病原菌分布及其药敏结果分析.docVIP

儿童社区获得性肺炎病原菌分布及其药敏结果分析 　　[摘要] 目的 探究并分析社区获得性肺炎患儿病原菌分布及其药敏结果，旨在为合理治疗社区获得性肺炎患儿提供参考依据。 方法 选择2011年1月～2012年12月湖北省十堰市妇幼保健院儿科收治的社区获得性肺炎患儿268例为研究对象，分别检测各患儿痰液、血液和咽拭子中的病毒及病原体检测，纸片扩散（KB）法进行药物敏感试验并进行结果分析，总结社区获得性肺炎患儿病原菌分布及其药敏结果。 结果 在268份送检标本中，159份检出病原菌，总检出率为59.33%，检出197株病原菌，其中，细菌78株，占39.59%；病毒42株，占21.32%；非典型病原体77株，占39.09%。38例存在混合感染，占病原菌感染患儿的23.90%，以细菌和病毒混合感染为主，流感嗜血菌、肺炎链球菌和大肠埃希菌对青霉素耐药较高，耐药率分别为57.36%、57.87%和52.79%，对头孢哌酮钠舒巴坦钠、阿莫西林克拉维酸钾均敏感，耐药率为0.00%。 结论 社区获得性肺炎患儿以肺炎支原体为最常见，其次为流感嗜血菌、肺炎链球菌和大肠埃希菌，对青霉素耐药较高，对头孢哌酮钠舒巴坦钠、阿莫西林克拉维酸钾均敏感。在临床工作中，要充分考虑到上述特征，选择合适的药物进行针对性的治疗，提高治疗效果，改善患者的预后。 　　[关键词] 儿童；社区获得性肺炎；病原菌；药敏试验 　　[中图分类号] R725.6 [文献标识码] A [文章编号] 1673-7210（2014）01（c）-0039-03 　　Analysis on the pathogenic bacteria distribution and drug susceptibility in children with community-acquired pneumonia 　　ZHANG Yunxia1 LI Wenbin2 　　1.Department of Pediatrics， Pediatrics and Child Health Hospital of Shiyan City， Hubei Province， Shiyan 442000， China； 2. Department of Pediatrics， Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology， Hubei Province， Wuhan 430074， China 　　[Abstract] Objective To investigate the pathogenic bacteria distribution and drug susceptibility in children with community-acquired pneumonia in order to provide reference for rational treatment of the community-acquired pneumonia children. Methods 268 children with community-acquired pneumonia from January 2011 to December 2012 were treated in the department of Pediatrics and Child Health Hospital of Shiyan City in Hubei Province were selected as the research objects， the virus and pathogens in sputum， blood and pharyngeal swab of children were detected respectively， drug sensitivity test were carried by KB method， and results were analyzed. Results 159 pathogenic bacterias were detected among the 268 sputum samples， the total detection rate of 59.33%， 197 strains were detected， in which 78 strains bacteria， accounting for 39.59%； 42 virus strains， accounted for 21.32%； 77 strains