紫色膏制备与临床应用.docVIP

紫色膏制备与临床应用 　　[摘要] 目的：探讨紫色膏的研制及其在机体深部感染、痈疽疮疡、痈疽已溃应用的临床效果。方法：将60例机体深部感染、痈疽疮疡、痈疽已溃患者随机分为实验组和对照组，各30例，实验组使用紫色膏敷料，直接敷于创面，每日或隔日换药1次，对照组用0.1%雷佛奴尔纱布常规换药。结果：实验组在伤口愈合时间、控制感染、机体创面的去腐生肌效果方面都明显优于对照组。结论：实验组效果优于对照组，紫色膏在治疗深部感染、痈疽疮疡，痈疽已溃等症方面疗效明显。 　　[关键词] 紫色膏；深部感染；痈疽疮疡；去腐生肌 　　[中图分类号] R283 [文献标识码]B [文章编号]1674-4721（2011）07（b）-104-02 　　 　　Preparation and clinical application of purple cream 　　HE Ke 　　Yulin Orthopaedic Hospital, Guangxi Zhuang Autonomous Region, Yulin 537000, China 　　[Abstract] Objective: To investigate the preparation of purple cream and its clinical effects in deep body infection, sore ulcer and ulcerous ulcer. Methods: 60 patients with deep body infection, sore ulcer and ulcerous ulcer were randomly divided into the experimental group and the control group, with 30 patients for each group. The experimental group was given the purple cream dressings, which was directly spread over the wound and changed every day or every other day. The control group was given 0.1% Leifonuer bandages and conventional dressings. Results: The experimental group was significantly better than the control group in wound healing time, infection control and removing decay and promoting tissue regeneration. Conclusion: The experimental group has better effects than the control group. The purple cream has obvious curative effects in the treatment of deep infection, sore ulcer and ulcerous ulcer. 　　[Key words] Purple cream; Deep infection; Sore ulcer; Remove decay and promote tissue regeneration 　　 　　本院是骨科专科医院，2010年住院患者超过10 000人次，中药制剂是本院专科治疗的一大特色，产品有20 种，其中紫色膏主要用于生肌、收敛、消肿排脓，在治疗机体深部感染、痈疽疮疡、痈疽已溃等方面取得满意疗效，现将研制方法和临床应用情况总结如下： 　　1资料与方法 　　1.1一般资料 　　共选择60例患者，其中，男38例，女22例，年龄18~55岁，术后感染20例，痈疽26例，压疮14例。上肢17例，下肢29例，背部8例，臀部6例。创面最大面积7.8 cm×6 cm，最小3 cm×2 cm。采用单盲法将患者随机分成两组，实验组30例（轻度感染伤口9处、中度感染伤口15处，重度感染伤口6处），创面应用紫色膏敷料；对照组30例（轻度感染伤口10处，中度感染伤口15处，重度感染伤口5处）创面应用0.1%雷佛奴尔纱布。两组患者的年龄、性别、部位、感染和痈疽疮疡的面积、程度等，差异无统计学意义（P0.05），具有可比性。 　　1.2方法 　　采用疗效对照法，比较紫色膏(本院制剂)和0.1%雷佛奴尔纱布的疗效。 　　1.2.1紫色膏（本院制剂）处方组成当归，白芷，甘草，紫草