c3d在人体正常肝组织和乙型病毒性肝炎肝硬化中glissons囊与纤维化区域表达的分析word格式论文.docxVIP

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c3d在人体正常肝组织和乙型病毒性肝炎肝硬化中glissons囊与纤维化区域表达的分析word格式论文.docx

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c3d在人体正常肝组织和乙型病毒性肝炎肝硬化中glissons囊与纤维化区域表达的分析word格式论文

优秀毕业论文精品参考文献资料 Study of Immunohistochemical Expression of C3d in Glissons Capsule and Fibrous Septa within Normal and Hepatitis B Cirrhosis of Human Liver Tissues Student: Hai Jian Huang Tutor: Zhi Yong Zheng, Chief Physician [Objectives] Abstract To observe expression of C3d in Glissons capsule (GC) within normal human liver tissue, and and to explore the reason, mechanism and significance of which of the deposition. To observe the expression of C3d in fibrous septum (FS) and GC within 76 hepatitis B cirrhosis (HBC) cases and 74 cases hepatitis B cirrhosis associated with hepatic carcinoma (HBC-HC), respectively, and to explore the source of FS fibers. To observe the inflammatory pathological characteristics of HBC and HBC-HC specimens, and to explore whether there are any relationship with follow-up and functional parameters. Observe the pathological features of portal activity (PA), and to explore its cinicathological significance. PA means the inflammation of or within GC wall. [Methods] Part Ⅰ 60 archived paraffin-formed normal liver specimens were obtained from the Department of Pathology, Fuzhou General Hospital of Nanjing Military Command of Chinese PLA from 2006 to 2010. All specimens were performed HE, reticular fiber-Masson staining and immunohistochemistry for IgG, IgM, IgA, C3d, C1q, and Fib staining, only C3d and CD21 staining for specimens of other organs of control group. Two cases of fresh normal adult liver tissues were choosed randomly to explore the C3d immune electron microscopy staining. Part Ⅱ 150 cases of archive paraffin specimens of liver transplant recipients, including 76 cases of Hepatitis B Cirrhosis (HBC) and 74 cases of Hepatitis B Cirrhosis associated with hepatic carcinoma (HBC-HC), were obtained from the Department of Pathology, Fuzhou General Hospital of Nanjing Military Command of Chinese PLA from 2008 to 2010. The subtype of liver cancer was 70 cases of HCC vs 4 cases of intrahepatic cholangiocarcinoma. All specimens