泮托拉唑对十二指肠溃疡治疗的疗效观察.docVIP

精品论文 参考文献 泮托拉唑对十二指肠溃疡治疗的疗效观察 齐桂杰1 王丽红2 　　(1辽宁省锦西石化医院 121000） 　　（2辽宁省绥中县医院腔镜科 125200) 　　【摘要】目的 探讨泮托拉唑治疗十二指肠溃疡溃疡的临床疗效。方法　将2011年4月～2013年9月我院接收的100例十二指肠溃疡患者为研究对象，随机平均分成两组，实验组与对照组，各50例。对照组患者给予雷尼替丁治疗，实验组患者给予泮托拉唑治疗，对比两组患者的临床治疗效果。结果　实验组患者经泮托拉唑治疗后，显效24例（48%），有效23例（46%），总有效率为94%，较对照组有明显提高；实验组患者疼痛评分也较对照组有显著性提高，两组比较存在显著性差异(Plt;0.05)。结论　对十二指肠溃疡患者给予泮托拉唑治疗可以显著改善患者的临床症状，促进十二指肠溃疡面的愈合，缓解患者的疼痛，提高临床治疗的有效率，是临床治疗十二指肠溃疡的有效方法，值得在临床上推广。 　　【关键词】泮托拉唑 十二指肠溃疡 疼痛评分 疗效观察 　　【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752（2014）06-0201-02 　　 　　The efficacy of Pantoprazole in the treatment of duodenal ulcer 　　【Abstract】 Objective: To evaluate the clinical efficacy of of Pantoprazole in the treatment of duodenal ulcer. Methods: 100 cases of duodenal ulcer patients in April 2011 - September 2013 in our hospital received for the study were randomly divided into two groups, the experimental group and the control group, each of 50 cases. Patients in the control group were treated with ranitidine therapy, and patients in the experimental group were treated with pantoprazole treatment, clinical outcomes were compared between two groups. Results: The experimental group patients after treatment with pantoprazole, cured in 24 cases (48%), effective in 23 cases (46%), total effective rate was 94%, which had significantly improvement compared with the control group. The pain scores of experimental group were also more significantly improved than the control group, which has a significant difference (P lt;0.05). Conclusion: Duodenal ulcer patients given pantoprazole therapy can significantly improve the clinical symptoms and promote healing of duodenal ulcer surface to ease the patients pain, and improve the clinical effectiveness of treatment. Itrsquo;s an effective method to treat duodenal ulcer, and should be promoted in clinical practice. 　　【Keywords】 pantoprazole duodenal ulcer pain scores Efficacy 　　十二指肠溃疡是常见的慢性消化系统疾病，多发于青年人群，主要是由于十二指肠球部粘膜组织被胃酸和胃蛋白酶分