DWI对宫颈癌的诊断及其与肿瘤分级的相关性初步研究.docVIP

精品论文 参考文献 DWI对宫颈癌的诊断及其与肿瘤分级的相关性初步研究 伍彩云 郭天畅 张婷 彭森 蔡崇岳 (东莞市石龙人民医院 523326) 【摘要】目的 探讨DWI及其ADC值在宫颈癌中的应用价值以及ADC值与肿瘤分级的相关性。方法 对36例宫颈癌患者及10例非宫颈肿瘤患者的宫颈进行常规MRI扫描、DWI成像及增强扫描，宫颈癌病例根据病理分级分为高分化组、中分化组及低分化组，比较正常宫颈各层与宫颈癌各组病灶的表观弥散系数（apparent diffusion coefficient，ADC）值。结果 正常宫颈ADC值显著高于宫颈癌的ADC值（Plt;0.01）,宫颈癌病例中低分化组与中分化及高分化组间的ADC值有差异（Plt;0.05）.结论 DWI及ADC值可有效的区分宫颈癌及正常宫颈，ADC值与宫颈癌的病理分级具有一定的相关性。 【关键词】子宫颈 宫颈肿瘤 磁共振成像 弥散加权成像 表现弥散系数 【中图分类号】R730.4 【文献标识码】A 【文章编号】2095-1752（2013）23-0394-03 Cervical Cancer:The Correlation between Tumor Grades and Diffusion-Weighted MR Imaging Wu Caiyun; Guo Tianchang; Zhang Ting; Peng Sen; Cai Chongyue Shilong Peoplersquo;s Hospital of Dongguan,Guangdong 【Abstract】Objective To determine the value of diffusion-weighted MRI and the apparent diffusion coefficient(ADC ) of cervical cancer and the the correlation between tumor grades and ADC.Methods Conventional MRI and DWI were performed in 36 females with surgically proven cervical cancer and 10 females with pathologically confirmed normal cervix .All the cases of cervical cancer were divided into well-differentiated, moderately differentiated and poorly differentiated. To compare the ADC value between the normal cervix and cervical cancer.Results The ADC values of cervical cancer were significantly lower than those of normal cervix.The ADC values of poorly differentiated group were significantly lower than those of moderately differentiated group and well-differentiated group.Conclusion DWI and ADC can differentiate beteween normal and cancerous cervix.ADC value has some dependablity with the grade of cervical cancer. 【Key words】cervix cervical cancer magnetic resonance imaging diffusion-weighted imaging apparent diffusion coefficient 子宫颈癌是最常见的妇科恶性肿瘤，好发于30-60岁的育龄妇女，目前临床诊断主要根据病史、症状、妇科检查和细胞学检查，其确诊依靠宫颈和宫颈管活组织检查，后者虽为最可靠的诊断依据，但是为有创性检查。对宫颈癌的早期诊断及病理分级将有利于临床治疗方案的制定，提高患者的生活质量及生存率。随着医学影像技术的发展，磁共振成像检查已较多的应用于宫颈癌的诊断，其价值也得到肯定。弥散加权成像，作为唯一能在体测定组织内水分子的扩散