不同治疗方案对老年慢性支气管肺炎患者肝损伤的比较.docVIP

精品论文 参考文献 不同治疗方案对老年慢性支气管肺炎患者肝损伤的比较 羊江鸿1 陈伟2 林雪妹1（通讯作者） （1儋州市那大镇医院 海南儋州 571700；2海口市第三人民医院 海南海口 571100） 【摘要】目的 探讨不同用药方案对老年慢性支气管肺炎患者肝脏的损伤情况，提高该类患者的诊治质量。方法 选择我院老年慢性支气管肺炎患者486例，随机分为实验组和对照组，两组患者同时采用头孢曲松钠、 丁氨卡纳、氨溴酸进行静脉点滴治疗，实验组在此基础上增加每日两次维生素C注射。对两组患者用药前、后进行血清谷丙转氨酶活性的测定以反映肝脏的损伤状况。利用统计学软件SPSS13.0对组间数据进行处理，Plt;0.05认为差异具有显著性。结果　实验组和对照组患者用药前ALT活性无明显差异，用药后两组患者血清ALT水平较用药前有所提高，但对照组用药后与用药前相比差异显著。两组患者用药后第7天对照组AST水平高于实验组，且组间差异具有统计学意义。结论　适量的维生素C对老年慢性支气管肺炎患者的肝脏具有一定的保护作用，有利于老年患者的康复。 【关键词】慢性支气管肺炎 维生素C 谷丙转氨酶 肝损伤 【中图分类号】R45 【文献标识码】A 【文章编号】2095-1752（2013）14-0105-02 Comparison of different therapeutic schemes for chronic liver damage in elderly patients with bronchial pneumonia 【Abstract】Objective To study the damage to liver by different therapeutic schemes for elerly chronic bronchial pneumonia patients and improve the treatment quality for them. Methods 486 patients with chronic bronchial pneumonia were chosen and randomly divided into experimental group and control group. All of them were treated with ceftriaxone sodium, Aminobutyric cana and Ammonium bromide.,while the experiment group were treated by vitamin C additionally. The damage to the liver were evaluated by the serum AlT activity and the data were analyzed by SPSS13.0.Results The ALT activity is similar before they are treated .The ALT activity of both of the two group promoted when they were treated, of which the control group were significantly different with that before treated(Plt;0.05). The ALT activity of the control group 7 day after treated is significantly higher than that of the experiment group(Plt;0.05). Conclusion Vitamin C is benifical for the protection of liver of the elderly patients with chronic bronchial pneumonia and worthy of application. 【Keywords】 alanine aminotransferase liver injury chronic bronchopneumonia vitamin C 随着社会的发展及老龄化社会的来临，老年群体的生存质量受到社会的广泛关注。老年患者的生存质量往往受到诸多慢性疾病的严重影响，而慢性呼吸系统疾病成为老年慢性病中比例较大的一类疾病[1]。慢性支气管肺炎是许多老年人易患病，由于患