文章full 2.pdfVIP

Original Article Comprehensive Geriatric Assessment and 2-Year Mortality in Elderly Patients Hospitalized for Heart Failure Carlos Rodriguez-Pascual, MD, PhD; Emilio Paredes-Galan, MD; Arturo Vilches-Moraga, MD; Ana Isabel Ferrero-Martinez, NP; Marta Torrente-Carballido, PsyD; Fernando Rodriguez-Artalejo, MD Background—In older adults hospitalized for heart failure, a poor score on a comprehensive geriatric assessment (CGA) is associated with worse prognosis during hospitalization and at 1 month after discharge. However, the association between the CGA score and long-term mortality is uncertain. Methods and Results—This is a prospective study of 487 patients aged ≥75 years admitted for decompensated heart failure. At discharge, a CGA score (range, 0–10) was calculated based on limitation in activities of daily living, mobility limitation, comorbidity, cognitive decline, and previous medication use. The analysis of the association between the D CGA score and 2-year subsequent mortality was performed with Cox regression and adjusted for the main confounders. o w A 1-point increase in the CGA score was associated with a 19% higher mortality (hazard ratio, 1.19; 95% confidence n l o interval, 1.11–1.27). Results were similar regardless of age, sex, left ventricular ejection fraction, and the coexistence a d e of atrial fibrillation, ischemic heart disease, or hypertensive cardiopathy. All components of the CGA score showed a d f r o consistent association with higher death risk: the hazard ratio (95% confidence interval) of mortality was 1.78 (1.25–2.54) m with ≥3 versus 0 limitati