antiplatelet effect and selective binding to cyclooxygenase (cox) by molecular docking analysis of flavonoids and lignans抗血小板效应和选择性结合环氧合酶(cox)通过分子对接和木酚素类黄酮的分析.pdfVIP

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antiplatelet effect and selective binding to cyclooxygenase (cox) by molecular docking analysis of flavonoids and lignans抗血小板效应和选择性结合环氧合酶(cox)通过分子对接和木酚素类黄酮的分析.pdf

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antiplatelet effect and selective binding to cyclooxygenase (cox) by molecular docking analysis of flavonoids and lignans抗血小板效应和选择性结合环氧合酶(cox)通过分子对接和木酚素类黄酮的分析

Int. J. Mol. Sci. 2007, 8, 830-841 International Journal of Molecular Sciences ISSN 1422-0067 © 2007 by MDPI /ijms Full Research Paper Antiplatelet Effect and Selective Binding to Cyclooxygenase (COX) by Molecular Docking Analysis of Flavonoids and Lignans 1 2 3 4 5 Chien-Ming Wu , Shu-Chun Wu , Wan-Jung Chung , Hsien-Cheng Lin , Kun-Tze Chen , Yu-Chian Chen 5 6 3 7 2,* , Mei-Feng Hsu , Jwu-Maw Yang , Jih-Pyang Wang and Chun-Nan Lin 1 Department of Physical Medicine and Rehabilitation, Yuans General Hospital, Kaohsiung 802, Taiwan 2 School of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan 3 Department of Biotechnology, Chia-Nan University of Pharmacy and Science, Tainan Hsien 717, Taiwan 4 School of Technology for Medical Science, Kaohsiung Medical University, Kaohsiung 807, Taiwan 5 Department of Biological Science and Technology, China Medical University, Taichung 404, Taiwan 6 Department of Biochemistry, China Medical University, Taichung 404, Taiwan 7 Department of Education and Research, Taichung Veterans General Hospital, Taiwan 407, Taiwan * Author to whom correspondence should be addressed; E-mail: lincna@.tw; Tel: (+886)7-3121101; Fax: (+886)7-5562365 Received: 30 July 2007; in revised form: 15 August 2007 / Accepted: 15 August 2007 / Published: 22