antioxidant status and immune activity of glycyrrhizin in allergic rhinitis mice甘草甜素的抗氧化状态和免疫活动小鼠过敏性鼻炎.pdfVIP

Int. J. Mol. Sci. 2011, 12, 905-916; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Antioxidant Status and Immune Activity of Glycyrrhizin in Allergic Rhinitis Mice Xiao-Lan Li 1,*, Ai-Guo Zhou 2, Li Zhang 3 and Wei-Jun Chen 4 1 Ear-Nose-Throat (ENT) Department of the 1th Hospital Associated to the ShiHeZi University, ShiHeZi city, XinJiang 832008, China 2 Acute Surgery Department of the 1th Hospital Associated to the ShiHeZi University, ShiHeZi city, XinJiang 832008, China; E-Mail: zhouag3@ 3 The Department of Traditional Chinese Medicine of the 1th Hospital Associated to the ShiHeZi University, ShiHeZi city, XinJiang 832008, China; E-Mail: zhanglshu@ 4 Medicament Section of the 1th Hospital Associated to the ShiHeZi University, ShiHeZi city, XinJiang 832008, China; E-Mail: chenwjshu@ * Author to whom correspondence should be addressed; E-Mail: lixlands@; Tel.: +86-993-2858-458; Fax: +86-993-2858-458. Received: 23 December 2010; in revised form: 5 January 2011 / Accepted: 7 January 2011 / Published: 26 January 2011 Abstract: Oxidative stress is considered as a major risk factor that contributes to increased lipid peroxidation and declined antioxidants in some degenerative diseases. Glycyrrhizin is widely used to cure allergic diseases due to its medicinal properties. In the present study, we evaluated the role of glycyrrhizin on lipid peroxidation and a