antioxidant protective effect of glibenclamide and metformin in combination with honey in pancreas of streptozotocin-induced diabetic rats的抗氧化保护作用,服用格列苯脲和二甲双胍结合蜂蜜在体外糖尿病大鼠胰腺.pdfVIP
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antioxidant protective effect of glibenclamide and metformin in combination with honey in pancreas of streptozotocin-induced diabetic rats的抗氧化保护作用,服用格列苯脲和二甲双胍结合蜂蜜在体外糖尿病大鼠胰腺
Int. J. Mol. Sci. 2010, 11, 2056-2066; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
Antioxidant Protective Effect of Glibenclamide and Metformin
in Combination with Honey in Pancreas of Streptozotocin-
Induced Diabetic Rats
Omotayo Owomofoyon Erejuwa 1,*, Siti Amrah Sulaiman 1, Mohd Suhaimi Abdul Wahab 1,
2 3 4
Kuttulebbai Nainamohammed Salam Sirajudeen , Md Salzihan Md Salleh and Sunil Gurtu
1 Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia,
16150 Kubang Kerian, Kelantan, Malaysia; E-Mails: sbsamrah@kb.usm.my (S.A.S.);
msuhaimi@kb.usm.my (M.S.A.W.)
2 Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia,
16150 Kubang Kerian, Kelantan, Malaysia; E-Mail: sirajuden@kb.usm.my
3 Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia,
16150 Kubang Kerian, Kelantan, Malaysia; E-Mail: matledpb@
4 School of Medicine and Health Sciences, Monash University Sunway Campus, Jalan Lagoon
Selatan, 46150, Bandar Sunway, Selangor, Malaysia; E-Mail: sgurtu@
* Author to whom correspondence should be addressed; E-Mail: erejuwa@;
Tel.: +609-7666-877; Fax: +609-7653-370.
Received: 9 March 2010; in revised form: 24 April 2010 / Accepted: 26 April 2010 /
Published: 5 May 2010
Abstract: Hyperglycemia exerts toxic e
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