有哪些信誉好的足球投注网站an interspecific nicotiana hybrid as a useful and cost-effective platform for production of animal vaccines一种间烟草混合作为一个有用的和具有成本效益的动物疫苗的生产平台.pdfVIP
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an interspecific nicotiana hybrid as a useful and cost-effective platform for production of animal vaccines一种间烟草混合作为一个有用的和具有成本效益的动物疫苗的生产平台
An Interspecific Nicotiana Hybrid as a Useful and Cost-
Effective Platform for Production of Animal Vaccines
1 1 2 3 1
Huai-Yian Ling , Aaron M. Edwards , Michael P. Gantier , Kathleen D. DeBoer , Alan D. Neale ,
4 1
John D. Hamill *, Amanda M. Walmsley *
1 School of Biological Sciences, Monash University, Clayton, Melbourne, Victoria, Australia, 2 Monash Institute of Medical Research, Centre for Cancer Research, Clayton,
Melbourne, Victoria, Australia, 3 Department of Anatomy and Development Biology, Monash University, Clayton, Melbourne, Victoria, Australia, 4 Department of Forest
and Ecosystem Science, University of Melbourne, Creswick, Victoria, Australia
Abstract
The use of transgenic plants to produce novel products has great biotechnological potential as the relatively inexpensive
inputs of light, water, and nutrients are utilised in return for potentially valuable bioactive metabolites, diagnostic proteins
and vaccines. Extensive research is ongoing in this area internationally with the aim of producing plant-made vaccines of
importance for both animals and humans. Vaccine purification is generally regarded as being integral to the preparation of
safe and effective vaccines for use in humans. However, the use of crude plant extracts for animal immunisation may enable
plant-made vaccines to become a cost-effective and efficacious approach to safely immunise large numbers of farm animals
against diseases such as avian influenza. Since the technology associated with genetic transformation and large-scale
propagation is very well established in Nicotiana, the genus has attributes well-suited for the production of plant-made
vaccines. However the presence of potentia
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