有哪些信誉好的足球投注网站altered dna binding and amplification of human breast cancer suppressor gene brca1 induced by a novel antitumor compound, [ru(η6-p-phenylethacrynate)cl2(pta)]改变dna结合和放大的人类乳腺癌的一种新颖的抗肿瘤化合物引起的抑制基因brca1,[俄文(η6-p-phenylethacrynate)(pta)氯].pdfVIP
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altered dna binding and amplification of human breast cancer suppressor gene brca1 induced by a novel antitumor compound, [ru(η6-p-phenylethacrynate)cl2(pta)]改变dna结合和放大的人类乳腺癌的一种新颖的抗肿瘤化合物引起的抑制基因brca1,[俄文(η6-p-phenylethacrynate)(pta)氯]
Int. J. Mol. Sci. 2012, 13, 13183-13202; doi:10.3390/ijms131013183
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
Altered DNA Binding and Amplification of Human Breast
Cancer Suppressor Gene BRCA1 Induced by a Novel Antitumor
Compound, [Ru(η6-p -phenylethacrynate)Cl (pta)]
2
Korawan Chakree 1, Chitchamai Ovatlarnporn 1, Paul J. Dyson 2 and Adisorn Ratanaphan 1,*
1 Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences,
Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand;
E-Mails: kchakree@hotmail.co.th (K.C.); lchitcha@pharmacy.psu.ac.th (C.O.)
2 Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology Lausanne
(EPFL), CH-1015 Lausanne, Switzerland; E-Mail: paul.dyson@epfl.ch
* Author to whom correspondence should be addressed; E-Mail: adisorn.r@psu.ac.th;
Tel.: +66-0-7428-8867; Fax: +66-0-7442-8239.
Received: 15 June 2012; in revised form: 25 August 2012 / Accepted: 8 October 2012 /
Published: 15 October 2012
6
Abstract: The ruthenium-based complex [Ru(η -p -phenylethacrynate)Cl (pta)]
2
(pta = 1,3,5-triaza-7-phosphatricyclo-[]decane), termed ethaRAPTA, is an
interest
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