第十章急性髓细胞白血病（Tenth chapter acute myeloid leukemia）.docVIP

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第十章急性髓细胞白血病（Tenth chapter acute myeloid leukemia）.doc

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第十章急性髓细胞白血病（Tenth chapter acute myeloid leukemia）

第十章急性髓细胞白血病（Tenth chapter acute myeloid leukemia） Tenth chapter acute myeloid leukemia ? Laboratory diagnosis of 8.M7 laboratory diagnosis diagnosis experiment of 7.M6 6.M5 5.M4 4.M3 laboratory diagnosis laboratory diagnosis laboratory diagnosis diagnosis experiment of 3.M2 2.M1 test in this chapter of the 1.M0 of the experimental diagnosis and M0 diagnosis: 1. experimental blood leukocyte count is low, low or normal platelets, with normocytic normochromic anemia. 2. bone marrow: the proliferation of bone marrow nucleated cells is relatively mild, the primitive cells are larger than 30%, and the erythroid and megakaryocyte lines have different degrees of hyperplasia and decrease. 3. cytochemical staining: POX and SB staining was negative or positive rate less than 3%. PAS and specific esterase staining were negative or weak positive. 4. immunological examination: immunocytochemistry, MP0 positive. Immunophenotype is expressed in myeloid lineage differentiation antigens CD13, CD33, CD14, CD15, and CD11b, with at least one positive. The expression of immature markers CD34, TdT, HLA-DR and B specific antigen and T lineage specific antigen could not be expressed. There is also immunocytochemical, MP0 negative, but expressed myeloid differentiation antigen. Two, M1 experimental diagnosis of 1. blood: anemia obvious, peripheral blood can be seen red blood cells, white blood cell count increased. In the blood samples, the primary granulocytes were predominant, while few patients showed no or few immature granulocytes. Moderate to severe thrombocytopenia. 2. bone marrow: bone marrow hyperplasia is extremely active or obviously active, and a few cases can increase life jump or even decrease. The granulocytes in the bone marrow were larger than 90% (NEC), and Auer corpuscles were found in the leukemic cells. The number of erythrocytes and megakaryocytes decreased significantly and lymphocytes decreased. 3. cytochemical staining: POX staining showed that there were at least