第 十二 章 特殊类型白血病（The twelfth chapter is special leukemia）.docVIP

第 十二 章 特殊类型白血病（The twelfth chapter is special leukemia） The twelfth chapter is special leukemia ? This chapter points 1. plasma cell leukemia 2. experimental diagnosis of hairy cell leukemia cell experimental diagnosis of mixed acute leukemia in 3. experimental diagnosis of plasma cell leukemia in laboratory diagnosis of plasma cell leukemia (PCL) clinically divided into primary plasma cell leukemia and secondary plasma cell leukemia. Primary plasma cell leukemia is an independent type of leukemia cells, characterized by abnormal white blood cell infiltrates, throughout the body tissues, and often accompanied by bleeding and amyloidosis, causing organ enlargement or dysfunction, clinical manifestations are anemia, fever, skin and mucous membrane hemorrhage, multiple organ infiltration, liver and splenomegaly, if the disease can have pleura invasion, pleural effusion, pleural effusion was seen in numerous plasma cells, if the violation of cardiac arrhythmia and heart failure can occur. Secondary plasma cell leukemia mainly from multiple myeloma, chronic lymphocytic leukemia, macroglobulinemia, leukemia and its pathological changes and clinical manifestations of primary plasma cell leukemia is similar. 1. blood: most cases had mild anemia were normocytic normochromic anemia, a low pigment, white blood cell count increased, up to (10 ~ 90) * 109 / L, including primitive and immature plasma cells, abnormal morphology. Platelet count decreased. 2. bone marrow: bone marrow hyperplasia is extremely active or markedly active, abnormal proliferation of plasma cells at all stages, including pulp cells, immature plasma cells, small plasma cells and reticular cell like plasma cells. The degree of maturation and morphology of plasma cells are very inconsistent, the morphology is generally small, round or oval, the nucleus is immature, the nucleoli are obvious, the chromatin is sparse, and the cytoplasm is unbalanced. 3. immunological tests: in addition to plasma cell associated