第 十一 章 慢性白血病（The eleventh chapter chronic leukemia）.docVIP

第 十一 章 慢性白血病（The eleventh chapter chronic leukemia） The eleventh chapter chronic leukemia ? This chapter points to 1. chronic myelogenous leukemia experimental diagnosis of 2. patients with chronic lymphocytic leukemia, a laboratory diagnosis of chronic myeloid leukemia diagnosis experiment 1. (1): red blood cells red blood cells and hemoglobin in early normal, even a few of Shao Zenggao, with the progression of the disease gradually showed mild and moderate decrease in blastic phase showed severe reduction. (2) white blood cells: the number of white blood cells increased significantly, the initial stage is generally 50 * 109/L, most in (100~300) * 109/L, up to 1000 * 109/L. Visible in each stage of the neutral granulocyte, fine grain and metamyelocyte increase is particularly prominent, rod-shaped particles and lobocytes increased, myeloblasts (I + II) less than 10% basophils can be as high as 10% to 20%, is one of the features of cml. Eosinophils and monocytes may also increase. With the progress of the disease, the original grain can be increased, the acceleration period can be more than 10%, more than 20% blast crisis. (3) platelet increased in l/3 ~ 1/2 of newly diagnosed cases, sometimes up to 1000 * 109/L, accelerated phase and blast crisis, platelets were decreased. 2. bone marrow: the proliferation of nucleated cells is extremely active, and the ratio of red to red is up to 10 to 50:1. In the proliferating granulocytes, the majority of neutrophils are young, immature and goblet cells. Granulocytes were less than 10%. Basophilic and eosinophilia, early proliferation of erythrocytes, suppression of late stage, increase of megakaryocytes, mild fibrosis of bone marrow. Accelerated phase and blast crisis, the original cells increased. CML is a clonal disease mutation of pluripotent stem cell level, thus to become more acute, acute leukemia, acute lymphocytic transformation, also can have kangbailin as the original single core, the original red cells, megakaryobl