有哪些信誉好的足球投注网站multiple sclerosis and ccsvi a population-based case control study多发性硬化和ccsvi以人群为基础的病例对照研究.pdfVIP
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multiple sclerosis and ccsvi a population-based case control study多发性硬化和ccsvi以人群为基础的病例对照研究
Multiple Sclerosis and CCSVI: A Population-Based Case Control Study 1 1 1 1 1 Francesco Patti , Alessandra Nicoletti , Carmela Leone , Silvia Messina , Emanuele D’Amico , 1 2 1 1 3 Salvatore Lo Fermo , Vincenza Paradisi , Elisa Bruno , Graziella Quattrocchi , Pierfrancesco Veroux , 4 4 1 Luigi Di Pino , Luca Costanzo , Mario Zappia * 1 Department DANA GF Ingrassia, Section of Neurosciences, University of Catania, Catania, Italy, 2 FIMG (Italian Federation of General Medicine), Catania Municipality Section, Catania, Italy, 3 Department of Vascular Surgery, University of Catania, Catania, Italy, 4 Department of Cardiology, University of Catania, Catania, Italy Abstract Background: Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to multiple sclerosis (MS). Objective: To evaluate the possible association between CCSVI and MS, using a population-based control design. Methods: A random cohort of 148 incident MS patients were enrolled in the study. We have also studied 20 patients with clinically isolated syndrome (CIS), 40 patients with other neurological diseases (OND), and 172 healthy controls. Transcranial (TCC) and Echo Color Doppler (ECD) were carried out in 380 subjects. A subject was considered CCSVI positive if $2 venous hemodynamic criteria were fulfilled. Results: CCSVI was present in 28 (18.9%) of the MS patients, in 2 (10%) of CIS patients, in 11 (6.4%) of the controls, and in 2 (5%) of the OND patients. A significant association between MS and CCSVI was found with an odds ratio
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