highly variable rates of genome rearrangements between hemiascomycetous yeast lineages高度可变利率之间的基因重组hemiascomycetous酵母血统.pdfVIP

Highly Variable Rates of Genome Rearrangements between Hemiascomycetous Yeast Lineages 1* 2,3 ´ ´ 4 5 1 Gilles Fischer , Eduardo P. C. Rocha , Frederic Brunet , Massimo Vergassola , Bernard Dujon ´ ´ ´ ´ ´ ´ ´ 1 Unite de Genetique Moleculaire des Levures (CNRS URA 2171, UFR927 Universite Pierre et Marie Curie), Departement de Structure et Dynamique des Genomes, Institut ´ ´ ´ ´ ´ ´ ´ Pasteur, Paris, France, 2 Unite Genetique des Genomes Bacteriens (CNRS URA 2171), Departement de Structure et Dynamique des Genomes, Institut Pasteur, Paris, France, ´ ´ 3 Atelier de Bioinformatique, Universite Pierre et Marie Curie, Paris, France, 4 Laboratoire de Biologie Moleculaire de la Cellule (CNRS UMR 5161, INRA LA 1237), Ecole ´ ´ ´ ´ ´ ´ Normale Superieure de Lyon, Lyon, France, 5 Unite de Genetique in silico (CNRS URA 2171), Departement de Structure et Dynamique des Genomes, Institut Pasteur, Paris, France Hemiascomycete yeasts cover an evolutionary span comparable to that of the entire phylum of chordates. Since this group currently contains the largest number of complete genome sequences it presents unique opportunities to understand the evolution of genome organization in eukaryotes. We inferred rates of genome instability on all branches of a phylogenetic tree for 11 species and calculated species