顺铂化疗中4种止吐方案的成本-效果分析.pdfVIP

·药物经济学· )1因伪化疗中 4 种止吆方素的成本一效果分析 张锦林铸(南通大学附属!中痛医院药剩科，南通市 226361) 中回分2每每阳75 A 文献标识码 B 文章编每 1672 - 2124(2酬11-0制3 02 摘 要 阔的:比较4 种止吆方案对预防顺钩化疗所致吸味的成本F 效采。方法:对 140 例接受舍顺钩化疗的肿瘤患者分为 4 组，分别用甲氛氯普麟(A 纽)、昂丹司凉(院组)、格拉司琼(C 纽)、托成司珠(0 级)预防化疗所致嗯吭，观察其疗效并进行成本再 放来分析。结果:4 纽止性方案有效率分别为 47.6% 、 76.5% 、 78.2% 、 80.6% ，每获得 1 个单位效果，4 纽方案所需成本分别为1.33 元、8.94 元、3.61 元和 1 l. 20 元，在 A 纽方案的基础上，每增加 1 个单位效果，B 怨、C 组和 D 级所追加的成本分别为 2l .47 元、7.14 元，和 25.44 元。结论:应用格拉司旅是较为合理的治疗方棠。 关键词 化疗;吸吆;成本-效果分析 Cost - etTectiveness Analysis of Four Antieme伽Schemωfor Patients Undergoing Cisplatin Chemotherapy ZHANG Jin-lin 伶 (Dept. of Phannacy , Nantong Tumor Hospital , Nar阳19 University , Nantong 226361 , China) ABSTRACf OBJECTIVE: To evaluate the ω供 - effectivene串串 of four different schemes in management of vomiting induced by císplatin chemotherapy. METHODS: A total of 140 patients undergoing cisplatin chemotherapy were assigned to receive one of the following 4 antiemetic drugs: Metoclopramide (Group A) , Ondansetron (Group B) , Granisetron (Group C) or Tropisetron (Group D). The therapeutic effects were monitored and the cost - effectiveness analyses were performed for the four treatment schemes. RESULTS: For the four groups , the effective rates were 47.6 % , 76.5 % , 78.2 % , and 80.6 % , respectively; the costs were 1.33 , 8.94 , 3.61 , and 11 .20 Yuan , respectively. As against Group A , the incremental costs for each unit increment of effectiveness in Group B , C , and D were 21.47 , 7.14 , and 25.44 yuan , re叩ectively. CONCLUSION: Granisetron (Group C) is the preferred one among the 4 schemes in man略;ement of vomiting induced by cisplatin chemotherapy . KEY WORDS Chemotherapy; Vomiting; Cost effectiveness analysis 顺销(OOP) 具有商效、广谐、很少与其它抗肿瘤药发生交 化疗方案根据病理结果确定:4 组患者选用联合化疗方 叉耐药等特点，在实体肿瘤治疗中应用广班，是目前最有效的