- 1、有哪些信誉好的足球投注网站(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。。
- 2、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 4、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 5、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
Effect of Occupational Manganese Exposure on Uric Acid Levels in Human Urine.pdf
222 BiomedEnvironSci,2011;24(3):222~227
OriginalArticle
EffectofOccupationalManganeseExposureonUricAcidLevelsinHuman
Urine
SUNXiaoMing’。,LIUYeWei,WANGZhenQuan,LIHongBing,LIUYun’。,and,DIDuoLong,
i.KeyLaboratoryofChem#tryofNorthwesternPlantResourcesandKyeLaboratoryIorNaturalMedicineof
GansuProvince,LanzhouInstituteofChemicalPhysics,ChineseAcademyofSciences,Lanzhou730000,Gansu,
China,2.GraduateUniversityoftheChineseAcademyofSciences,Beijing100049,China,3.InstituteofNutrition
andFoodHygiene,SchoolofPublicHealth,LanzhouUniversity,Lanzhou730000,Gansu,China
Abstract
Objective Toinvestigatetheeffectoflong—termandlow—leveloccupationalMnexposureontheleve
ofuricacid(UA)inhumanurine.
Methods Inthisstudy,65volunteerswererecruited,whowereworkingonweldingandfoundrywork
inanplantinGansuprovince,China.Additionally,29controIsampieswerecollectedfrOm individuals
who did nothave any history ofexcessive Mn exposure.An improved high pefformance Iiquid
chromatographysystemequippedwithadiode—arraydetector(HPLC—DAD)methodwasdevelopedto
determinetheUAfeveIinhumanurine.ASpectraAA220AtomicAbsorption5pectrophotometerfAAS)
wasusedtomeasuretheMnIeveIintheurine.
Results Theanalyticalmethodwasvalidatedforconcentrationsrangingfrom 3.82-45.84ug/mLwith
acceptable accuracy,precision,and recovery Overall,the UA levelsofMnexposuresampleswere
significantlylowerthanthatofcontrolsamples(P0.0s).
Conclusion ThepracticalmethoddevelopedhereissuitableforbothroutinemonitoringofUA levelin
humanurineandmetabolism research.Long·term andlow—leveloccupationalMnexposuremayleadto
alowerUAlevelinurine,andUAmightbeanindicatoroftheearlystageofmanganism.
Keywords:High·performanceliquidchromatography;Uricacid;OccupationalMnexposure
BiomedEnvironSci,2011;
您可能关注的文档
- 1927-1937年中国参加国际电信会议述论.pdf
- 2000—2010年中国经济发展的实证研究——基于菲利普斯曲线与奥肯定律的分析.pdf
- 2005—2010年氯酸盐主要产品进出口统计数据汇总及分析.pdf
- 4-氨基4-甲基哌啶二对甲苯磺酸盐的合成.pdf
- 4个引进甜菜品种DNA指纹图谱的建立.pdf
- A HYBRID FIXED POINT RESULT FOR LIPSCHITZ HOMOMORPHISMS ON QUASI-BANACH ALGEBRAS.pdf
- A MULTI-CRITERIA DECISION MAKING PROCEDURE BASED ON INTERVAL-VALUED INTUITIONISTIC FUZZY BONFERRONI MEANS.pdf
- A New and Efficient Procedure for Synthesis of 1,5-Benzodiazepine Derivatives in Solution and under Solvent-Free Conditions.pdf
- A NOVEL MIXED INTEGER PROGRAMMING FORMULATION AND PROGRESSIVELY STOCHASTIC SEARCH FOR CAPACITATED LOT SIZING.pdf
- A Porous Organic-inorganic Hybrid Compound Constructed from Polyoxovanadium Borate Anions,Dinuclear Na Sites and Metal-organic Units.pdf
- Effect of San'ao Decoction(三拗汤) on the Airway Inflammation and Hyperresponsiveness in a Murine Model of Lipopolysaccharide-enhanced Asthma.pdf
- Effects and Mechanisms of Actions of Chinese Herbal Medicines for Asthma.pdf
- Eight-Regularity of Types of Crop Capacity Structure of Winter Wheat.pdf
- Epidemiological Survey and Analysis on an Outbreak of Gastroenteritis due to Water Contamination.pdf
- ERP系统中基于构件的流程重构的研究和实现.pdf
- ESTIMATED AND EXACT SYSTEM RELIABILITIES OF A MAINTAINABLE COMPUTER NETWORK.pdf
- Eucalyptus中基于能量消耗的调度算法研究.pdf
- Experimental Study on the Molecular Mechanism of Anthraquinone Cathartics in Inducing Melanosis Coli.pdf
- Factors Associated with Generic and Disease-specific Quality of Life in Epilepsy.pdf
- Farmer Participatory Breeding - The Foster Parent in the Breeding of Dioscorea spp. in Ghana.pdf
文档评论(0)