眼肿瘤学--概念与进展课件.pdfVIP

OCULAR ONCOLOGY CONCEPT AND ADVANCES  Eyelids  Conjunctiva  Intraocular  Orbital  Phakomatosis  Most common eyelid malignancy  Nevus-like nodule, solidly, grow very slowly, ulcer, ‘mouse-bitten ‘ appearance  Local extension,metastasis rarely  Sensitve to radiation  SEBACEOUS GLAND CARCINOMA (SGC)  Mostly origin from Meibomian gland （Meibomian gland carcinoma ）  Elderly women, ’chalazion’,subcutaeous nodule,white mass from tarsal side  Metastasize frequently  Excision reconstruction  Chalazion in elderly need regular pathological examination Cutler-Beard pro. 80% upper lid defect after resection, 22ms later OCULAR SURFACE SQUAMOUS NEOPLASM （OSSN）  Squamous cell origin  Degeneration/carcinoma in situ /squamous cell carcinoma  Sunshine/ultraviolet/hpv SCC  Fissure area,limbus especially,weeks to years  Multiple appearance: nodule/patch/mist/inflammation  Papilloma  Carcinoma in situ (Bowen disease)  Intraepithelial carcinoma in situ  Squamous cell carcinoma  Color brown 65% tan 19% nonpigmented 16%  Discrete  Elevated  Cysts  Stationary  Marginal nevus cilia  Kissing nevus cosmesis MALIGNANT CHANGES OF NEVUS  A newly nevus in an elderly people  Recorded growth (area thickness)  cyst or cilia diminished  Corneal extension  palpebral conjunctiva  Obvious feeding vessel  Satellite  Recurrence after excision PRIMARY ACQUIRED MELANOSIS （PAM）  Elderly/middle age, caucasian A typical PAM  Acquired yellow to brown patch /Unilateral/discrete/irregular/obscure margin  G