超敏C反应蛋白等指标检测在慢性阻塞性肺疾病急性加重期的临床价（临床医学论文资料）.docVIP

超敏C反应蛋白等指标检测在慢性阻塞性肺疾病急性加重期的临床价（临床医学论文资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：超敏C反应蛋白等指标检测在慢性阻塞性肺疾病急性加重期的临床价 1 1 材料与方法 3 2 结果 4 3 讨论 4 文2：无创通气对慢性阻塞性肺疾病急性加重期的疗效观察 5 一、资料与方法 6 二、结果 8 参考文摘引言： 12 原创性声明（模板） 13 文章致谢（模板） 14 正文 超敏C反应蛋白等指标检测在慢性阻塞性肺疾病急性加重期的临床价（临床医学论文资料） 文1：超敏C反应蛋白等指标检测在慢性阻塞性肺疾病急性加重期的临床价 Clinical Value of Index Detection likeHigh Seitivity C - reactive Protein in AECOPD A Xuande 【Abstract】Objective: to observe High Seitivity C-Reactive Protein (hs-CRP) of serum and relevance with index like lung function; to study clinical value of index detection like hs-CRP of the patients with Acute Exacerbation Chronic Obstructive Pulmonary Disease (AECOPD). Method: to detect the content of hs-CRP of serum， FEV1/FVC of lung function during the fit second， blood gas analysis and white cell count， etc. of 65 patients with AECOPE and their comparison before admission and remission after the treatment. Results: the level of hs-CRP of the patients with AECOPD: before admission ± mg/l， remission after the treatment ±/l， normal control group ± mg/l. The level of hs-CRP of the patients with AECOPD is obviously higher than of the normal control group. There is a statistical significance (P) with the difference. The concentration of hs-CRP after the treatment is still higher than of the normal control group， but there is no statistical significance. There is negative correlation between the change of hs-CRP and the level of FEV1/FVC， PO2 and positive correlation between the change of hs-CRP and the level of PCO2， WBC. Conclusion: hs-CRP detection can be used as a seitive index in diagnosis and severity assessment of AECOPD. 【Key words】High Seitivity C-Reactive Protein， COPD， acute exacerbation. 慢性阻塞性肺疾病(COPD)是一种具有不完全可逆气流受限为特征的疾病，是重要的公共卫生问题，目前是世界上第四大死因。广大学者已经认识到，急性发作是影响COPD患者转归的重要因素，反复急性加重可导致COPD患者住院及病死率增加[1]。由于COPD患者多为老年人，常伴免疫功能低下，营养不良，在急性加重期时血白细胞往往不高，缺乏特异的检查手段。C反应蛋白是最有价值的急性时相蛋白，超敏C反应蛋白（Supeeitivity-C reactive protein，hs-CRP）检测具更高灵敏度，在疾病发作6h内含量即迅速升高