腹腔镜手术治疗进展期远端胃癌近期疗效及安全性的研究.docVIP

腹腔镜手术治疗进展期远端胃癌近期疗效及安全性的研究 　　【摘要】 目的 探讨腹腔镜手术治疗进展期远端胃癌的近期临床疗效及安全性。方法 62例进展期远端胃癌患者， 采用随机数字表法将其分为研究组和对照组， 各31例， 研究组行腹腔镜远端胃癌根治术， 对照组行开腹远端胃癌根治术， 综合比较两组患者术中、术后情况， 并发症发生率及5年生存率。结果 研究组手术时间长于对照组（P0.05）；研究组术中出血量、肠道功能恢复时间、住院时间均显著优于对照组（P0.05）；研究组术后并发症发生率为6.45%， 显著低于对照组的19.35%（P0.05）；研究组5年生存率51.6%显著高于对照组29.0%（P0.05）。结论 腹腔镜远端胃癌根治术治疗进展期远端胃癌疗效显著， 并发症少， 恢复快。 　　【关键词】 腹腔镜；进展期远端胃癌；安全性 　　DOI：10.14163/j.cnki.11-5547/r.2015.22.015 　　Research of short-term curative effect and safety of laparoscope surgery in the treatment of distal gastric cancer in progressive stage CHEN Jian-xiong， LI Liang-huan， XU Ma-chuan. Department of General Surgery， Guangdong Yangjiang City People’s Hospital， Yangjiang 529500， China 　　【Abstract】 Objective To investigate short-term curative effect and safety of laparoscope surgery in the treatment of distal gastric cancer in progressive stage. Methods A total of 62 patients with distal gastric cancer in progressive stage were divided by random number table into research group and control group， with 31 cases in each group. The research group received laparoscope radical operation for distal gastric cancer， and the control group received radical operation by laparotomy. Comprehensive comparisons were made on intraoperative and postoperative status， incidences of complications， and five-year survival rate between the two groups. Results The research group had longer operation time（P0.05）， and obviously better intraoperative bleeding volume， intestinal function recovery time， and hospital stay than the control group （P0.05）. The research group had much lower incidence of postoperative complications as 6.45% than 19.35% of the control group （P0.05）. The research group also had obviously higher 5-year survival rate as 51.6% than 29.0% of the control group （P0.05）. Conclusion Laparoscope radical operation for distal gastric cancer provides significant effect in treating distal gastric cancer in progressive stage， along with few complications and quick rehabilitation