大剂量川芎嗪治疗急性脑梗死35例诊治体会.docVIP

精品论文 参考文献 大剂量川芎嗪治疗急性脑梗死35例诊治体会 武汉市黄陂区人民医院重症科 湖北武汉 430300 摘要：目的：研究分析大剂量川芎嗪治疗急性脑梗死的临床治疗效果。方法：选取本院自2015午3月-2016年4月间在我科治疗的急性脑梗死患者70例，随机分成研究组和对照组各35例，对照组采用一般剂量的川芎嗪进行治疗，而研究组则采用大剂量川芎嗪，后对比观察两组患者的临床疗效。结果：研究组总有效率为96.67%，对照组为93.33%，差异不具有统计学意义（Pgt;0.05）。但比较两组患者的基本治愈率，研究组明显较对照组高（63.33%vs36.67%），差异具有显著性（Plt;0.05）。两组患者不良反应比较。差异不具有统计学意义，Pgt;0.05。结论：研究表明，采用大剂量川芎嗪治疗急性脑梗死疗效更为显著。 关键词：急性脑梗死；川芎嗪；大剂量；诊治体会 Large dose of ligustrazine in treatment of acute cerebral infarction diagnosis and treatment of 35 cases （in Wuhan city Huangpi District Peoples Hospital of Hubei，Wuhan 430300） [Abstract] Objective：To study the clinical therapeutic effect of high dose ligustrazine in the treatment of acute cerebral infarction.Methods：in our hospital from 2015 afternoon March 2016 years 4 months in the hospital geriatrics treatment of 70 cases of patients with acute cerebral infarction were randomly divided into study group and control group with 35 cases in each，control group were treated with Ligustrazine dose，while the study group is used large dose of Ligustrazine，to observe the clinical efficacy of the two groups of patients.Results：the total effective rate of the study group was 96.67%，and the control group was 93.33%，the difference was not statistically significant（Pgt;0.05）.But the basic cure rate of the two groups were compared，the study group was significantly higher than the control group（63.33%vs36.67%），and the difference was significant（Plt;0.05）.Comparison of adverse reactions in two groups of patients.The difference was not statistically significant，Pgt;0.05.Conclusion：the research shows that the treatment of acute cerebral infarction with high dose of Ligustrazine is more effective. [Key words] acute cerebral infarction；Ligustrazine；high dose；diagnosis and treatment 脑梗死是脑动脉粥样硬化、血管内膜损伤、局部血栓形成等多种因素导致的动脉管腔狭窄、阻塞，进一步导致脑组织缺血缺氧坏死[1]。本病一般起病较急骤，经过治疗后一般还存在一定程度的神经功能障碍，其严重影响患者的正常生活[2]。目前对于本病的治疗主要采用药物治疗，本文选取本院自2015年3月-2016年4月间在本院老年病科进行治疗的急性脑梗死患者70例，就大剂量川芎嗪治疗急性脑梗死的临床治疗效果进行研究分析，详细研究结果如下。