有哪些信誉好的足球投注网站biological activities of aqueous and organic extracts from tropical marine sponges水和有机提取物的生物活性热带海洋海绵.pdfVIP
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biological activities of aqueous and organic extracts from tropical marine sponges水和有机提取物的生物活性热带海洋海绵
Mar. Drugs 2010, 8, 1550-1566; doi:10.3390/md8051550 OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Article Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges Kristina Sepčić 1, Silke Kauferstein 2, Dietrich Mebs 2 and Tom Turk 1,* 1 Department of Biology, Biotechnical Faculty, University of Ljubljana, Večna pot 111, 1000 Ljubljana, Slovenia 2 Institute of Legal Medicine, University of Frankfurt, Kennedyallee 104, 60596 Frankfurt, Germany * Author to whom correspondence should be addressed; E-Mail: tom.turk@bf.uni-lj.si; Tel.: +386 1 4233388; Fax: +386 1 2573390. Received: 3 March 2010; in revised form: 26 March 2010 / Accepted: 2 April 2010 / Published: 28 April 2010 Abstract: We report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested for hemolytic, hemagglutinating, antibacterial and anti-acetylcholinesterase (AChE) activities, as well as their ability to inhibit or activate cell protein phosphatase 1 (PP1). The most interesting activities were obtained from extracts of Ircinia felix , Pandaros acanthifolium, Topsentia ophiraphidites, Verongula rigida and Neofibularia nolitangere . Aqueous and organic extracts of I. felix and V. rigida showed strong antibacterial activity. Topsentia aqueous and some organic e
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