whole genome sequencing and a new bioinformatics platform allow for rapid gene identification in d. melanogaster ems screens全基因组测序和生物信息学平台允许快速识别基因d .腹ems屏幕.pdfVIP
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whole genome sequencing and a new bioinformatics platform allow for rapid gene identification in d. melanogaster ems screens全基因组测序和生物信息学平台允许快速识别基因d .腹ems屏幕
Biology 2012, 1, 766-777; doi:10.3390/biology1030766 OPEN ACCESS biology ISSN 2079-7737 /journal/biology Article Whole Genome Sequencing and a New Bioinformatics Platform Allow for Rapid Gene Identification in D. melanogaster EMS Screens 1 1 1 1 Michael A. Gonzalez , Derek Van Booven , William Hulme , Rick H. Ulloa , 1 2 3 2 Rafael F. Acosta Lebrigio , Jeannette Osterloh , Mary Logan , Marc Freeman and Stephan Zuchner 1,* 1 Dr. John T. Macdonald Foundation Department of Human Genetics and John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA; E-Mails: mgonzalez15@ (M.A.G.); dvanbooven@ (D.V.B.); whulme@ (W.H.); rulloa@ (R.H.U.); racosta2@ (R.F.A.L.) 2 Department of Neurobiology University of Massachusetts Medical School, Howard Hughes Medical Institute, Worcester, MA, USA; E-Mails: jeannette.osterloh@ (J.O.); marc.freeman@ (M.F.); 3 Jungers Center for Neurosciences Research, Department of Neurology Oregon Health Science University, Portland, OR, USA; E-Mail: loganm@ * Author to whom correspondence should be addressed; E-Mail: szuchner@; Tel.: 305-243-2281; Fax: 305-243-2703. Received: 5 October 2012; in revised form: 14 November 2012 / Accepted: 20 November 2012 / Published: 5 December 2012 Abstract: Forward genetic screens in Drosophila melanogaster using
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