antinociceptive and anti-inflammatory effects of octacosanol from the leaves of sabicea grisea var. grisea in miceantinociceptive和抗炎作用的主的叶子sabicea菌var.菌在小鼠体内.pdfVIP
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antinociceptive and anti-inflammatory effects of octacosanol from the leaves of sabicea grisea var. grisea in miceantinociceptive和抗炎作用的主的叶子sabicea菌var.菌在小鼠体内
Int. J. Mol. Sci. 2012, 13, 1598-1611; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
Antinociceptive and Anti-Inflammatory Effects of Octacosanol
from the Leaves of Sabicea grisea var. grisea in Mice
1 1 2
Anderson Marques de Oliveira , Lucia M. Conserva , Jamylle N. de Souza Ferro ,
Fabíola de Almeida Brito 2, Rosângela P. Lyra Lemos 3 and Emiliano Barreto 2,*
1 Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, Maceió/AL 57072-970,
Brazil; E-Mails: andermarx@.br (A.M.O.); lmc@qui.ufal.br (L.M.C.)
2 Laboratório de Biologia Celular, Universidade Federal de Alagoas, Maceió/AL 57072-970, Brazil;
E-Mails: mylla_champras@ (J.N.S.F.); fabiolabrito@ (F.A.B.)
3 Instituto do Meio Ambiente do Estado de Alagoas, Maceió/AL 57017-320, Brazil;
E-Mail: rosalyralemos@
* Author to whom correspondence should be addressed; E-Mail: emilianobarreto@;
Tel.: +55-82-3214-1704; Fax: +55-82-3221-2501.
Received: 21 December 2011; in revised form: 26 January 2012 / Accepted: 30 January 2012 /
Published: 2 February 2012
Abstract: Sabicea species are used in the Amazon for treatment of fever and malaria,
which suggests that its chemical constituents may have some effect on pain and
inflammation. Phytochemical an
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