临床标本耐甲氧西林金黄色葡萄球菌分布及药敏研究.docVIP

临床标本耐甲氧西林金黄色葡萄球菌分布及药敏研究[摘要] 目的：了解医院内感染耐甲氧西林金黄色葡萄球菌（MRSA）的耐药情况， 指导临床合理使用抗菌药物。方法：将本院2008年1月～2010年11月送检的标本进行回顾性分析。结果：共检出金黄色葡萄球菌380株，MRSA检出率为61.8%（235/380）。MRSA对常用抗菌药物有较高的耐药率，其中，青霉素、庆大霉素、红霉素、诺氟沙星、左氧氟沙星耐药率较高，为62%～99%，万古霉素、替考拉宁的敏感性为100.0%。结论：医院内耐甲氧西林金黄色葡萄球菌耐药率高，应加强耐药监测，合理使用抗菌药物。 [关键词] 耐甲氧西林金黄色葡萄球菌；耐药性；抗菌药物；耐药监测 [中图分类号] R927.1 [文献标识码] C[文章编号] 1674-4721（2011）04（a）-070-02 Clinical samples of methicillin-resistant Staphylococcus aureus analysis of distribution and drug sensitivity LIU Huirong1, LIN Dingzhong2* 1. Maternity and Child Care Centers in Huiyang Area of Huizhou City, Guangdong Province, Huizhou 516211, China; 2. Department of Division, the People’s Hospital of Huiyang District in Huizhou City, Guangdong Province, Huizhou 516211, China [Abstract] Objective: Understand nosocomial infections resistant dermatologists (MRSA) drug resistance, guide clinical rational use of antimicrobial agents. Methods: 2008 January to 2010 November strains specimens were retrospectively analyzed in our hospital. Resurts: 380 strains were detected by staphylococcus aureus, Methicillin-resistant staphylococcus aureus was 61.8% (235/380). Methicillin-resistant staphylococcus aureus to commonly used antimicrobial agents had higher resistance, including penicillin, gentamycin, erythromycin, obvious, levofloxacin resistance was higher, ranging from 62 percent-99 percent, vancomycin, TiKao pull ning sensitivity of 100.0%. Conclusion: Methicillin-resistant staphylococcus aureus resistant to high drug resistance surveillance in hospital. We should be strengthened, rational use of antimicrobial drugs. [Key words] Methicillin-resistant staphylococcus aureus; Drug-resistance of bacteria; Antibiotics; Resistance monitoring 金黄色葡萄球菌（staphylococcus aureus，Sau）是医院和社区获得性感染的最常见病原体之一，在全球范围内有很高的发病率和死亡率。随着广谱抗菌药物广泛应用或滥用，细菌耐药问题日益严峻。其中耐甲氧西林金黄色葡萄球菌（methicillin-resistant staphylococcus aureus，MRSA）的耐药问题已成为各方关注热点之一。为了解本院临床标本分离的金黄色葡萄球菌对常用抗菌药物耐药情况，为临床合理使用抗菌药物提供依据，现总结报道如下： 1 资料与方法 1.1 一般