空腹血胰岛素、葡萄糖比值作为β细胞功能指数的可能性(The possibility of fasting serum insulin and glucose ratios as a function index of beta cells).docVIP
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空腹血胰岛素、葡萄糖比值作为β细胞功能指数的可能性(The possibility of fasting serum insulin and glucose ratios as a function index of beta cells)
空腹血胰岛素、葡萄糖比值作为β细胞功能指数的可能性(The possibility of fasting serum insulin and glucose ratios as a function index of beta cells) The possibility of fasting serum insulin and glucose ratios as a function index of beta cells 2010-02-23 Li Guangwei Pan Xiaoren [Abstract] Objective To investigate the possibility of fasting plasma insulin and glucose ratio (FINS/FPG) as a group to study the function index of pancreatic beta cell, and compare it with other indexes in the literature. Methods in 281 patients with normal glucose tolerance (NGT) and 181 patients with impaired glucose tolerance (IGT), fasting plasma glucose and insulin were measured 1 hours and 2 hours after fasting and 75 g of glucose. According to the postprandial blood glucose level 2 hours increased 0.556mmol/L, then IGT from low to high blood glucose is divided into 6 sub groups, t test and variance test to determine the five kinds of commonly used beta cell function index FINS/FPG and the literature distinguish between NGT and IGT, and IGT blood glucose levels in different subgroups of beta cell function the difference. Results OGTT 1 hours plasma insulin and glucose ratio (INS1/PG1), OGTT insulin, blood glucose value ratio (INS/ PG) and Homa model in 20 * FINS/ (FPG-3.5) can distinguish from the change of beta cell function in NGT, IGT, but no one can identify IGT blood glucose levels with beta cell function in Asia the difference between the groups. After adjusting the influence of insulin sensitivity, they have different abilities to distinguish the tendency of beta cell function in these populations. Conclusion the effect of using the beta cell function index to adjust insulin sensitivity; the FINS/FPG beta cell function was assessed in epidemiological studies, the resolution is not inferior to Homa in model 20 * FINS (FPG-3.5). [keyword] impaired glucose tolerance, beta cell function, insulin, blood glucose Possibility, of, using, the, fasting, blood, insulin/glucose, ratio, an, as, index, of, beta, cell, L
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