有哪些信誉好的足球投注网站mycobacterium tuberculosis lipolytic enzymes as potential biomarkers for the diagnosis of active tuberculosis结核分枝杆菌分解脂肪的酶作为潜在生物标志物的诊断活动性结核病.pdfVIP
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mycobacterium tuberculosis lipolytic enzymes as potential biomarkers for the diagnosis of active tuberculosis结核分枝杆菌分解脂肪的酶作为潜在生物标志物的诊断活动性结核病
Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis 1,5 ´ 5 3 4 ´ 4 Belinda Brust , Melanie Lecoufle , Edouard Tuaillon , Luc Dedieu , Stephane Canaan , Viviane Valverde5, Laurent Kremer 1,2* ´ 1 Laboratoire de Dynamique des Interactions Membranaires Normales et Pathologiques, Universites de Montpellier II et I, CNRS UMR 5235, Montpellier, France, 2 INSERM, ´ ´ ´ ´ DIMNP, Montpellier, France, 3 INSERM U1058, Universite de Montpellier I, Departement de Bacteriologie-Virologie, Institut de Recherche en Biotherapie, Centre Hospitalier ´ Universitaire de Montpellier, Montpellier, France, 4 CNRS UPR 9025, Universite Aix-Marseille, Enzymologie Interfaciale et Physiologie de la Lipolyse, Marseille, France, 5 Clinical Microbiology Division, Bio-Rad Laboratories, Steenvoorde, France Abstract Background: New diagnosis tests are urgently needed to address the global tuberculosis (TB) burden and to improve control programs especially in resource-limited settings. An effective in vitro diagnostic of TB based on serological methods would be regarded as an attractive progress because immunoassays are simple, rapid, inexpensive, and may offer the possibility to detect cases missed by standard sputum smear microscopy. However, currently available serology tests for TB are highly variable in sensitivity and specificity. Lipolytic enzymes
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