有哪些信誉好的足球投注网站muscle mitochondrial atp synthesis and glucose transportphosphorylation in type 2 diabetes肌肉线粒体atp合成和葡萄糖transportphosphorylation 2型糖尿病.pdfVIP
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muscle mitochondrial atp synthesis and glucose transportphosphorylation in type 2 diabetes肌肉线粒体atp合成和葡萄糖transportphosphorylation 2型糖尿病
PLoS MEDICINE Muscle Mitochondrial ATP Synthesis and Glucose Transport/Phosphorylation in Type 2 Diabetes 1,2 2,3 2,3 2 4 3 Julia Szendroedi , Albrecht I. Schmid , Marek Chmelik , Christian Toth , Attila Brehm , Martin Krssak , 1 1 1 2,4* Peter Nowotny , Michael Wolzt , Werner Waldhausl , Michael Roden 1 Department of Internal Medicine 3, University of Vienna, Vienna, Austria, 2 Karl-Landsteiner Institute of Endocrinology and Metabolism, Vienna, Austria, 3 High-Field Magnetic Resonance Centre of Excellence, Medical University of Vienna, Vienna, Austria, 4 First Medical Department, Hanusch Hospital, Vienna, Austria Funding: This study was supported A B S T R A C T by grants from the Austrian Science Foundation (P15656), Austrian National Bank (OENB 11459), European Foundation for the Study of Background Diabetes (EFSD, Novo Nordisk Type 2 Diabetes Grant), Herzfelder Family Muscular insulin resistance is frequently characterized by blunted increases in glucose-6- ¨ Trust, Hochschuljubilaumsstiftung phosphate (G-6-P) reflecting impaired glucose transport/phosphorylation. These abnormalities Vienna, and an unrestricted grant by likely relate to excessive intramyocellular lipids and mitochondrial dysfunction. We Novo Nordisk and Baxter to MR. The funders had no role in study design, hypothesized that alterations in insulin action and mitochondrial function should
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