high burden of impetigo and scabies in a tropical country热带国家的高负担的脓疱病和疥疮.pdfVIP

High Burden of Impetigo and Scabies in a Tropical Country 1 1 2 3 1 Andrew C. Steer *, Adam W. J. Jenney , Joseph Kado , Michael R. Batzloff , Sophie La Vincente , Lepani Waqatakirewa2, E. Kim Mulholland1,4,5, Jonathan R. Carapetis1,4 1 Centre for International Child Health, University of Melbourne, Melbourne, Australia, 2 Fiji Ministry of Health, Suva, Fiji Islands, 3 Queensland Institute of Medical Research, Brisbane, Australia, 4 London School of Hygiene and Tropical Medicine, London, United Kingdom, 5 Menzies School of Health Research, Charles Darwin University, Darwin, Australia Abstract Background: Impetigo and scabies are endemic diseases in many tropical countries; however the epidemiology of these diseases is poorly understood in many areas, particularly in the Pacific. Methodology/Principal Findings: We conducted three epidemiological studies in 2006 and 2007 to determine the burden of disease due to impetigo and scabies in children in Fiji using simple and easily reproducible methodology. Two studies were performed in primary school children (one study was a cross-sectional study and the other a prospective cohort study over ten months) and one study was performed in infants (cross-sectional). The prevalence of active impetigo was 25.6% (95% CI 24.1–27.1) in primary school children and 12.2% (95% CI 9.3–15.6) in infants. The prevalence of scabies was 18.5% (95% CI 17.2–19.8) in primary school children and 14.0% (95% CI 10.8–17.2) in infants. The incidence density of active impetigo, group A streptococcal (GAS) impetigo, Staphylococcus aureus impetigo and scabies was 122, 80, 64 and 51 cases per 100 child-years respectively. Impetigo was strongly associated with scabies infestation (o