有哪些信誉好的足球投注网站genetic variations in hspa8 gene associated with coronary heart disease risk in a chinese populationhspa8基因的遗传变异与冠心病风险的中国人口.pdfVIP
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genetic variations in hspa8 gene associated with coronary heart disease risk in a chinese populationhspa8基因的遗传变异与冠心病风险的中国人口
Genetic Variations in HSPA8 Gene Associated with Coronary Heart Disease Risk in a Chinese Population 1,2 1 1 1 1 2 3 Meian He , Huan Guo , Xiaobo Yang , Li Zhou , Xiaomin Zhang , Longxian Cheng , Hesong Zeng , 4 5 1 Frank B. Hu , Robert M. Tanguay , Tangchun Wu * 1 Department of Occupational and Environmental Health and the Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2 Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 3 Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 4 Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, 5 Laboratory of Cellular and ´ ´ Developmental Genetics, Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Universite Laval, Quebec, Canada Abstract Background: There is ample evidence that Hsp70 takes part in the progress of coronary heart disease (CHD). This implies that genetic variants of Hsp70 genes such as HSPA8 (HSC70) gene might contribute to the development of CHD. The present study aimed to investigate whether certain genetic variants of HSPA8 gene are associated with CHD in Han Chinese people. Methodology/Principal Findings: A total of 2006 subjects (1003 CHD cases and 1003 age- and sex- mat
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