有哪些信誉好的足球投注网站genetic variation of the human α-2-heremans-schmid glycoprotein (ahsg) gene associated with the risk of sars-cov infection遗传变异的人类α-2-heremans-schmid糖蛋白(ahsg)基因与冠状病毒感染的风险.pdfVIP
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genetic variation of the human α-2-heremans-schmid glycoprotein (ahsg) gene associated with the risk of sars-cov infection遗传变异的人类α-2-heremans-schmid糖蛋白(ahsg)基因与冠状病毒感染的风险
Genetic Variation of the Human a-2-Heremans-Schmid Glycoprotein (AHSG) Gene Associated with the Risk of SARS-CoV Infection 1. 1,5. 2,6. 1. 1 3 4 Xiaohui Zhu , Yan Wang , Hongxing Zhang , Xuan Liu , Ting Chen , Ruifu Yang , Yuling Shi , 3 1 1 2,6 2,6 2,6 1 Wuchun Cao , Ping Li , Qingjun Ma , Yun Zhai , Fuchu He , Gangqiao Zhou *, Cheng Cao * 1 State Key Laboratory of Pathogen and Bio-Security, Beijing Institute of Biotechnology, Beijing, China, 2 State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, China, 3 State Key Laboratory of Pathogen and Bio-Security, Institute of Microbiology and Epidemiology, Beijing, China, 4 General Hospital of Guangzhou Command, PLA, Guangzhou, China, 5 General Hospital of Beijing Command, PLA, Beijing, China, 6 National Engineering Research Center for Protein Drugs, Beijing, China Abstract Genetic background may play an important role in the process of SARS-CoV infection and SARS development. We found several proteins that could interact with the nucleocapsid protein of the SARS coronavirus (SARS-CoV). a-2-Heremans- Schmid Glycoprotein (AHSG), which is required for macrophage deactivation by endogenous cations, is associated with inflammatory regulation. Cytochrome P450 Family 3A (CYP4F3A) is an v-oxidase that inactivates Leukotriene B4 (LTB4) in human neutrophils and the liver. We investigated the association between the polymorphisms of these two inflammation- associated genes and SARS development. The linkage disequilibri
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